caa a22 4500 445298049 CHVBK 20180317142547.0 cr unu---uuuuu 170323e20100601xx s 000 0 eng 10.1007/s12070-010-0037-1 doi (NATIONALLICENCE)springer-10.1007/s12070-010-0037-1 Survival patterns in patients with carcinoma base of tongue treated with external beam irradiation and salvage surgery [Elektronische Daten] [Jaimanti Bakshi, Naresh Panda, Sushmita Ghoshal, Vikas Nehru] Objective: The current study was designed to assess the treatment results and survival in the patients with carcinoma of base of tongue that were treated with primary radiotherapy, radiotherapy with chemotherapy and salvage surgery when indicated. Design: A prospective study was carried out in 78 cases of carcinoma of the base of tongue between 1995 and 1999. Methods: The majority of cases belonged to stage IV 60/78 (76.92%) as per AJCC staging. Radiotherapy in the dose of 60 Gy was given primarily to the patients with stage III tongue base cancer. Patients with early stage IV cancer were given split course radiotherapy followed by assessment for surgery. For the patients with advanced stage IV disease with poor general condition, palliative radiotherapy of 24 Gy with or without palliative chemotherapy was given. 15 patients were subjected to salvage surgery in the form of radical neck dissection alone (8 cases), extended total laryngectomy with neck dissection (3 cases), extended total laryngectomy (2 cases) and extended supraglottic laryngectomy with RND in 2 cases. Results: Two and 5 years Kaplan — Meier actuarial survival rates were 45% and 10% respectively with local control rates equivalent to survival rates. All surviving patients maintained good function and quality-of-life with few tolerable side effects. Conclusions: External beam radiotherapy with salvage surgery results in satisfactory local and regional control in stage III and IV carcinoma base of tongue. Association of Otolaryngologists of India, 2010 Base of tongue nationallicence Radiation therapy nationallicence Salvage surgery nationallicence Survival nationallicence Bakshi Jaimanti Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India aut Panda Naresh Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India aut Ghoshal Sushmita Radiation Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India aut Nehru Vikas Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India aut Indian Journal of Otolaryngology and Head & Neck Surgery Springer-Verlag 62/2(2010-06-01), 142-147 0019-5421 62:2<142 2010 62 12070 https://doi.org/10.1007/s12070-010-0037-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12070-010-0037-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bakshi Jaimanti Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India aut NATIONALLICENCE 700 1- Panda Naresh Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India aut NATIONALLICENCE 700 1- Ghoshal Sushmita Radiation Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India aut NATIONALLICENCE 700 1- Nehru Vikas Department of Otolaryngology and Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India aut NATIONALLICENCE 773 0- Indian Journal of Otolaryngology and Head & Neck Surgery Springer-Verlag 62/2(2010-06-01), 142-147 0019-5421 62:2<142 2010 62 12070 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer