caa a22 4500 445298456 CHVBK 20180317142549.0 cr unu---uuuuu 170323e20101201xx s 000 0 eng 10.1007/s12013-010-9114-z doi (NATIONALLICENCE)springer-10.1007/s12013-010-9114-z Interference Microscopy in Cell Biophysics. 1. Principles and Methodological Aspects of Coherent Phase Microscopy [Elektronische Daten] [Vladimir Tychinsky, Alexander Tikhonov] The purpose of our tandem publications is to review the applications of the coherent phase microscopy to cell biophysics. In this article, we briefly consider the fundamentals and methodological aspects of the coherent phase microscopy (CPM). One of important advantages of this method is a high sensitivity of CPM images to changes in physical-chemical properties of biological samples. The optical path length difference (OPLD), measured with CPM instruments in different domains of an object, serves as the informative optical parameter used for visualization of individual cells or intracellular organelles. Metabolically dependent variations of CPM images reflect changes in the functional state of biological objects. In the next article, we review results of CPM studies of different cells and intracellular energy-transducing organelles. Springer Science+Business Media, LLC, 2010 Coherent phase microscopy nationallicence Phase thickness nationallicence Refractivity nationallicence Phase image processing nationallicence CPM : Coherent phase microscopy or coherent phase microscope nationallicence DPM : Dynamic phase microscopy nationallicence OPLD : Optical path length difference nationallicence h ( x , y ) : 2D distribution of the OPDL values in the image plane (x,y) nationallicence h ( x ) : The OPDL profile along a scan-line nationallicence Δ h : The height of the OPDL profile nationallicence Δ n : Refractivity nationallicence Tychinsky Vladimir Moscow State Institute for Radioengineering, Electronics and Automation, prosp. Vernadskogo 78, 119454, Moscow, Russia aut Tikhonov Alexander Faculty of Physics, M.V. Lomonosov Moscow State University, 119992, Moscow, Russia aut Cell Biochemistry and Biophysics Humana Press Inc 58/3(2010-12-01), 107-116 1085-9195 58:3<107 2010 58 12013 https://doi.org/10.1007/s12013-010-9114-z text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12013-010-9114-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tychinsky Vladimir Moscow State Institute for Radioengineering, Electronics and Automation, prosp. Vernadskogo 78, 119454, Moscow, Russia aut NATIONALLICENCE 700 1- Tikhonov Alexander Faculty of Physics, M.V. Lomonosov Moscow State University, 119992, Moscow, Russia aut NATIONALLICENCE 773 0- Cell Biochemistry and Biophysics Humana Press Inc 58/3(2010-12-01), 107-116 1085-9195 58:3<107 2010 58 12013 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer