caa a22 4500 445298596 CHVBK 20180317142550.0 cr unu---uuuuu 170323e20100101xx s 000 0 eng 10.1007/s12013-009-9068-1 doi (NATIONALLICENCE)springer-10.1007/s12013-009-9068-1 The Influence of 1800MHz GSM-like Signals on Hepatic Oxidative DNA and Lipid Damage in Nonpregnant, Pregnant, and Newly born Rabbits [Elektronische Daten] [Arin Tomruk, Goknur Guler, Aylin Dincel] The aim of our study is to evaluate the possible biological effects of whole-body 1800MHz GSM-like radiofrequency (RF) radiation exposure on liver oxidative DNA damage and lipid peroxidation levels in nonpregnant, pregnant New Zealand White rabbits, and in their newly borns. Eighteen nonpregnant and pregnant rabbits were used and randomly divided into four groups which were composed of nine rabbits: (i) Group I (nonpregnant control), (ii) Group II (nonpregnant-RF exposed), (iii) Group III (pregnant control), (iv) Group IV (pregnant-RF exposed). Newborns of the pregnant rabbits were also divided into two groups: (v) Group V (newborns of Group III) and (vi) Group VI (newborns of Group III). 1800MHz GSM-like RF radiation whole-body exposure (15min/day for a week) was applied to Group II and Group IV. No significant differences were found in liver 8OHdG/106 dG levels of exposure groups (Group II and Group IV) compared to controls (Group I and Group III). However, in Group II and Group IV malondialdehyde (MDA) and ferrous oxidation in xylenol orange (FOX) levels were increased compared to Group I (P<0.05, Mann-Whitney). No significant differences were found in liver tissue of 8OHdG/106 dG and MDA levels between Group VI and Group V (P>0.05, Mann-Whitney) while liver FOX levels were found significantly increased in Group VI with respect to Group V (P<0.05, Mann-Whitney). Consequently, the whole-body 1800MHz GSM-like RF radiation exposure may lead to oxidative destruction as being indicators of subsequent reactions that occur to form oxygen toxicity in tissues. Humana Press Inc., 2009 Radiofrequency nationallicence Pregnant nationallicence 8OHdG nationallicence MDA nationallicence Liver nationallicence Rabbit nationallicence Tomruk Arin Department of Biophysics, Gazi University, Faculty of Medicine, Gazi Üniversitesi Tıp Fakültesi Biyofizik Abd, Dekanlık Binası 5. Kat, 06500, Besevler, Ankara, Turkey aut Guler Goknur Department of Biophysics, Gazi University, Faculty of Medicine, Gazi Üniversitesi Tıp Fakültesi Biyofizik Abd, Dekanlık Binası 5. Kat, 06500, Besevler, Ankara, Turkey aut Dincel Aylin Department of Biochemistry, Gazi University, Faculty of Medicine, 06500, Ankara, Turkey aut Cell Biochemistry and Biophysics Humana Press Inc 56/1(2010-01-01), 39-47 1085-9195 56:1<39 2010 56 12013 https://doi.org/10.1007/s12013-009-9068-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12013-009-9068-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tomruk Arin Department of Biophysics, Gazi University, Faculty of Medicine, Gazi Üniversitesi Tıp Fakültesi Biyofizik Abd, Dekanlık Binası 5. Kat, 06500, Besevler, Ankara, Turkey aut NATIONALLICENCE 700 1- Guler Goknur Department of Biophysics, Gazi University, Faculty of Medicine, Gazi Üniversitesi Tıp Fakültesi Biyofizik Abd, Dekanlık Binası 5. Kat, 06500, Besevler, Ankara, Turkey aut NATIONALLICENCE 700 1- Dincel Aylin Department of Biochemistry, Gazi University, Faculty of Medicine, 06500, Ankara, Turkey aut NATIONALLICENCE 773 0- Cell Biochemistry and Biophysics Humana Press Inc 56/1(2010-01-01), 39-47 1085-9195 56:1<39 2010 56 12013 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer