caa a22 4500 445298928 CHVBK 20180317142551.0 cr unu---uuuuu 170323e20101101xx s 000 0 eng 10.1007/s11940-010-0094-5 doi (NATIONALLICENCE)springer-10.1007/s11940-010-0094-5 Newer Anticonvulsant Medications in Pediatric Neurology [Elektronische Daten] [Michael Quach, Abdul Mazin, James Riviello Jr] Opinion statement: Antiepileptic drugs (AEDs) are the mainstay of treatment for recurrent seizures. Uncontrolled seizures may cause medical, developmental, and psychological disturbances. The medical practitioner should thus strive to eliminate or minimize seizures. Treatment advances in epilepsy include 1) identification of the basic mechanisms of epilepsy and action of AEDs, 2) the introduction of new AEDs, and 3) the use of neurostimulation, including vagus nerve stimulation. Treatment with AEDs involves balancing each AED's efficacy against its side effects. In some patients, effective AEDs must be discontinued because of intolerable side effects. Although all AEDs have a proven efficacy, the choice of AEDs should be based on better efficacy for individual seizure types or epilepsy syndromes. Side effects also differ from drug to drug and must be taken into account. This article focuses on studies and expert opinion consensus to guide the choice of AEDs. Springer Science+Business Media, LLC, 2010 Quach Michael Texas Children's Hospital, 6621 Fannin, CC1250, 77030, Houston, TX, USA aut Mazin Abdul Section of Pediatric Neurology, University of Chicago, 5721 South Maryland Avenue, MC 3055, Rm. C-391, 60637, Chicago, IL, USA aut Riviello Jr James Texas Children's Hospital, 6621 Fannin, CC1250, 77030, Houston, TX, USA aut Current Treatment Options in Neurology Current Science Inc. 12/6(2010-11-01), 518-528 1092-8480 12:6<518 2010 12 11940 https://doi.org/10.1007/s11940-010-0094-5 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11940-010-0094-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Quach Michael Texas Children's Hospital, 6621 Fannin, CC1250, 77030, Houston, TX, USA aut NATIONALLICENCE 700 1- Mazin Abdul Section of Pediatric Neurology, University of Chicago, 5721 South Maryland Avenue, MC 3055, Rm. C-391, 60637, Chicago, IL, USA aut NATIONALLICENCE 700 1- Riviello Jr James Texas Children's Hospital, 6621 Fannin, CC1250, 77030, Houston, TX, USA aut NATIONALLICENCE 773 0- Current Treatment Options in Neurology Current Science Inc 12/6(2010-11-01), 518-528 1092-8480 12:6<518 2010 12 11940 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer