caa a22 4500 445299002 CHVBK 20180317142551.0 cr unu---uuuuu 170323e20100501xx s 000 0 eng 10.1007/s11940-010-0072-y doi (NATIONALLICENCE)springer-10.1007/s11940-010-0072-y Parkinson's Psychosis [Elektronische Daten] [Laura Zahodne, Hubert Fernandez] Opinion statement: Psychosis is a leading reason for nursing home placement of patients with Parkinson's disease (PD). It may also be the single greatest stressor for caregivers of PD patients, it is generally persistent, and its presence markedly increases the risk of mortality. For these reasons, it is essential to recognize and appropriately treat psychosis in PD. Treatment of psychotic symptoms should be initiated after potential medical and environmental causes of delirium (eg, infection) have been eliminated or addressed. Initial pharmacologic changes should include limiting the patient's anti-PD medications to those that are necessary to preserve motor function (ie, eliminating adjunctive agents). Should that fail, an atypical antipsychotic agent is the treatment of choice. Clozapine is presently the gold standard, and quetiapine represents another option because of its ease of use and good tolerability profile. Emerging treatment options include the use of acetylcholinesterase inhibitors, antidepressants, and cognitive behavioral therapy. This article reviews what is currently known about treatment strategies in PD psychosis. Springer Science+Business Media, LLC, 2010 Zahodne Laura Department of Clinical & Health Psychology, University of Florida, P.O. Box 100165, 32610-0165, Gainesville, FL, USA aut Fernandez Hubert Department of Neurology, University of Florida, P.O. Box 100236, 32610-0236, Gainesville, FL, USA aut Current Treatment Options in Neurology Current Science Inc. 12/3(2010-05-01), 200-211 1092-8480 12:3<200 2010 12 11940 https://doi.org/10.1007/s11940-010-0072-y text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11940-010-0072-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zahodne Laura Department of Clinical & Health Psychology, University of Florida, P.O. Box 100165, 32610-0165, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Fernandez Hubert Department of Neurology, University of Florida, P.O. Box 100236, 32610-0236, Gainesville, FL, USA aut NATIONALLICENCE 773 0- Current Treatment Options in Neurology Current Science Inc 12/3(2010-05-01), 200-211 1092-8480 12:3<200 2010 12 11940 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer