caa a22 4500 44529907X CHVBK 20180317142551.0 cr unu---uuuuu 170323e20100701xx s 000 0 eng 10.1007/s11940-010-0073-x doi (NATIONALLICENCE)springer-10.1007/s11940-010-0073-x Tourette's Disorder [Elektronische Daten] [Gholson Lyon, David Shprecher, Barbara Coffey, Roger Kurlan] Opinion statement: Tourette's disorder (TD) is a common childhood-onset neuropsychiatric disorder characterized by chronic motor and vocal tics. TD frequently occurs with other neuropsychiatric disorders, such as attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD), and may contribute to reduced quality of life and disability. Currently available treatments to reduce tics are limited by variable clinical response and frequent adverse effects. They include alpha-2 agonists, antipsychotics (first and second generation), tetrabenazine, benzodiazepines, and habit reversal therapy. Some new and emerging (but unproven) treatments are also discussed, including topiramate and dopamine agonists. In addition, there is increasing interest in deep brain stimulation, but this is not yet ready for general use. Springer Science+Business Media, LLC, 2010 Lyon Gholson Atlantic Neuroscience Institute, Overlook Hospital, 99 Beauvoir Avenue, 07902, Summit, NJ, USA aut Shprecher David Atlantic Neuroscience Institute, Overlook Hospital, 99 Beauvoir Avenue, 07902, Summit, NJ, USA aut Coffey Barbara Atlantic Neuroscience Institute, Overlook Hospital, 99 Beauvoir Avenue, 07902, Summit, NJ, USA aut Kurlan Roger Atlantic Neuroscience Institute, Overlook Hospital, 99 Beauvoir Avenue, 07902, Summit, NJ, USA aut Current Treatment Options in Neurology Current Science Inc. 12/4(2010-07-01), 274-286 1092-8480 12:4<274 2010 12 11940 https://doi.org/10.1007/s11940-010-0073-x text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11940-010-0073-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lyon Gholson Atlantic Neuroscience Institute, Overlook Hospital, 99 Beauvoir Avenue, 07902, Summit, NJ, USA aut NATIONALLICENCE 700 1- Shprecher David Atlantic Neuroscience Institute, Overlook Hospital, 99 Beauvoir Avenue, 07902, Summit, NJ, USA aut NATIONALLICENCE 700 1- Coffey Barbara Atlantic Neuroscience Institute, Overlook Hospital, 99 Beauvoir Avenue, 07902, Summit, NJ, USA aut NATIONALLICENCE 700 1- Kurlan Roger Atlantic Neuroscience Institute, Overlook Hospital, 99 Beauvoir Avenue, 07902, Summit, NJ, USA aut NATIONALLICENCE 773 0- Current Treatment Options in Neurology Current Science Inc 12/4(2010-07-01), 274-286 1092-8480 12:4<274 2010 12 11940 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer