caa a22 4500 445299266 CHVBK 20180317142552.0 cr unu---uuuuu 170323e20100301xx s 000 0 eng 10.1007/s11940-010-0058-9 doi (NATIONALLICENCE)springer-10.1007/s11940-010-0058-9 Treatment of Chronic Inflammatory Demyelinating Polyneuropathy [Elektronische Daten] [Eliza Robertson, Peter Donofrio] Opinion statement: Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired, immune-mediated, non-length-dependent polyradiculoneuropathy that is progressive or relapsing over a period of at least 8weeks, often evolving over time to a relatively symmetric pattern. Although the exact pathogenesis is unclear, it is thought to be mediated by both cellular and humoral reaction to the peripheral nerve myelin sheath involving nerve roots and proximal and distal nerves. Early medical treatment of CIDP is important to prevent axonal loss occurring as a secondary effect of progressive demyelination. Only three treatments for CIDP have demonstrated benefit in randomized controlled studies: corticosteroids, plasma exchange, and intravenous immunoglobulin. About 25% of patients fail to respond to these treatments or respond inadequately. These treatments have similar efficacy but differ significantly in cost and adverse effects. These factors are considered in treatment selection. Springer Science+Business Media, LLC, 2010 Robertson Eliza Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, A-0118 MCN, 37232-2551, Nashville, TN, USA aut Donofrio Peter Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, A-0118 MCN, 37232-2551, Nashville, TN, USA aut Current Treatment Options in Neurology Current Science Inc. 12/2(2010-03-01), 84-94 1092-8480 12:2<84 2010 12 11940 https://doi.org/10.1007/s11940-010-0058-9 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11940-010-0058-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Robertson Eliza Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, A-0118 MCN, 37232-2551, Nashville, TN, USA aut NATIONALLICENCE 700 1- Donofrio Peter Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, A-0118 MCN, 37232-2551, Nashville, TN, USA aut NATIONALLICENCE 773 0- Current Treatment Options in Neurology Current Science Inc 12/2(2010-03-01), 84-94 1092-8480 12:2<84 2010 12 11940 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer