caa a22 4500 445303859 CHVBK 20180317142606.0 cr unu---uuuuu 170323e20100501xx s 000 0 eng 10.1007/s12274-010-1041-1 doi (NATIONALLICENCE)springer-10.1007/s12274-010-1041-1 Direct electrochemistry of cytochrome c at a hierarchically nanostructured TiO2 quantum electrode [Elektronische Daten] [Li Liu, Ning Wang, Xia Cao, Lin Guo] Monodisperse TiO2 nanoparticles and urchin-like hierarchical TiO2 nanospheres assembled with ultrathin quantum nanowires (about 2 nm) have been synthesized by a simple template-free wet chemical method. The morphology, structure, and crystallinity of the TiO2 nanomaterials were investigated by field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), and high resolution transmission electron microscopy (HRTEM). Electrochemical measurements with the hierarchically nanostructured TiO2 nanospheres as an electrode showed much better reversibility for direct electrochemistry of cytochrome c (cyt c) and much higher sensitivity than for an electrode composed of the monodisperse TiO2 nanoparticles. The excellent performance of the hierarchical TiO2 nanospheres may result from a quantum size effect, and their favorable nanostructure (with the presence of an abundance of both uniform macropores and mesopores), excellent structural stability and high specific surface area. The relative ionic strength had significant effect on the direct electrochemistry. Very high ionic strengths relative to cyt c concentration (I/c) induced a conformational change of cyt c on the nanostructure-coated electrode, from the native state to a partially unfolded one in 25 mmol/L phosphate buffer solution (pH 6.8). Tsinghua University Press and Springer-Verlag Berlin Heidelberg, 2010 Hierarchically nanostructured TiO2 nationallicence cytochrome c nationallicence ionic strength nationallicence bioelectrochemistry nationallicence Liu Li School of Chemistry and Environment, Beijing University of Aeronautics and Astronautics, 100191, Beijing, China aut Wang Ning School of Chemistry and Environment, Beijing University of Aeronautics and Astronautics, 100191, Beijing, China aut Cao Xia School of Material Science and Engineering, Jiangsu University of Science and Technology, 212003, Jiangsu, China aut Guo Lin School of Chemistry and Environment, Beijing University of Aeronautics and Astronautics, 100191, Beijing, China aut Nano Research Tsinghua Press 3/5(2010-05-01), 369-378 1998-0124 3:5<369 2010 3 12274 https://doi.org/10.1007/s12274-010-1041-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12274-010-1041-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Liu Li School of Chemistry and Environment, Beijing University of Aeronautics and Astronautics, 100191, Beijing, China aut NATIONALLICENCE 700 1- Wang Ning School of Chemistry and Environment, Beijing University of Aeronautics and Astronautics, 100191, Beijing, China aut NATIONALLICENCE 700 1- Cao Xia School of Material Science and Engineering, Jiangsu University of Science and Technology, 212003, Jiangsu, China aut NATIONALLICENCE 700 1- Guo Lin School of Chemistry and Environment, Beijing University of Aeronautics and Astronautics, 100191, Beijing, China aut NATIONALLICENCE 773 0- Nano Research Tsinghua Press 3/5(2010-05-01), 369-378 1998-0124 3:5<369 2010 3 12274 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer