caa a22 4500 445306262 CHVBK 20180317142614.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00404-009-1272-0 doi (NATIONALLICENCE)springer-10.1007/s00404-009-1272-0 Effect of umbilical vein blood flow on perinatal outcome of fetuses with lean and/or hypo-coiled umbilical cord [Elektronische Daten] [Manal El behery, Amal Nouh, Amal Alanwar, Abdalla Diab] Objective: To evaluate the effect of umbilical vein (UV) blood flow measured by color-directed pulsed-wave Doppler on perinatal outcome of fetuses with lean and/or hypocoiled umbilical cord after 24weeks of gestation. Methods: Two hundred and forty-four women with singleton fetus after 24weeks of gestation were studied. Umbilical cord area, umbilical vessel cross-sectional area and antenatal umbilical coiling index (UCI) were calculated and compared with Doppler parameters including UV blood flow volume in ml/min/kg, UV peak systolic velocity in cm/s, and umbilical artery pulsatility index. Results: Thirty-eight (15.5%) fetuses had lean umbilical cord (area<10th percentile). A significant difference between fetuses with and those without lean cord was found in terms of: UCI (0.17±0.06 vs. 0.35±0.08, P<0.001), cord cross-sectional area (89.6±11.7 vs. 198.7±33.7mm2, P<0.001), Wharton's jelly amount (36.5±11.2 vs. 125.2±34.1mm2, P<0.001), UV blood flow (83.4±15.8 vs. 131.0±19.8ml/min/kg, P<0.001), and UV blood flow mean velocity (8.6±3.7 vs. 12.1±2.8cm/s, P<0.05). A significant positive correlation was found between antenatal UCI and UV blood flow (r=0.73, P<0.001). Conclusion: Fetuses with lean and/or hypo-coiled umbilical cord showed a noticeable decrease in UV blood flow of sufficient magnitude that could affect fetal growth, and this could explain the higher prevalence of fetal intrapartum complications in growth-restricted fetuses. Springer-Verlag, 2009 Lean umbilical cord nationallicence Umbilical vein nationallicence Blood flow nationallicence Perinatal outcome nationallicence El behery Manal Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut Nouh Amal Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut Alanwar Amal Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut Diab Abdalla Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut Archives of Gynecology and Obstetrics Springer-Verlag 283/1(2011-01-01), 53-58 0932-0067 283:1<53 2011 283 404 https://doi.org/10.1007/s00404-009-1272-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-009-1272-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- El behery Manal Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut NATIONALLICENCE 700 1- Nouh Amal Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut NATIONALLICENCE 700 1- Alanwar Amal Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut NATIONALLICENCE 700 1- Diab Abdalla Obstetrics and Gynecology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/1(2011-01-01), 53-58 0932-0067 283:1<53 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer