caa a22 4500 445306270 CHVBK 20180317142614.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00404-009-1275-x doi (NATIONALLICENCE)springer-10.1007/s00404-009-1275-x "At fingers' ends”: risk factors and perinatal outcome of pregnancies complicated by digital malformations [Elektronische Daten] [Tamar Tzur, Eyal Sheiner, Adi Weintraub, Moshe Mazor, Arnon Wiznitzer, Eldad Silberstein, Gershon Holcberg, Tali Silberstein] Objective: To identify the incidence, risk factors, and perinatal outcome of newborns with congenital finger or toe (digital) anomalies. Method: A retrospective study including all neonates born at a tertiary medical center during 2001-2006 with congenital digital anomalies was conducted. The comparison group consisted of newborns without such anomalies born during the same period. Results: Of 115,876 newborns delivered during the study period, 360 (31 per 10,000) were diagnosed with digital anomalies. Polydactyly was the most common diagnosis (n=263; 73% of digital anomalies). Associated anomalies in these patients were congenital heart malformations (n=93; 25.8% of the newborns with congenital digital anomalies), central nervous system anomalies (n=17; 4.7%), and musculoskeletal anomalies (n=13; 3.6%). Newborns with congenital digital anomalies were more likely to be males (62.2 vs. 37.8%; P<0.001), and of a Bedouin Arab descent compared to Jewish ethnicity (61.4 vs. 38.6%; P=0.004). Significantly higher rates of severe pre-eclampsia, recurrent abortions, transverse lie, and low birth-weight (<2,500g) infants were found among newborns with digital anomalies. Conclusions: The incidence of digital anomalies can vary according to the population characteristics. It may be associated with other skeletal and non-skeletal malformations as well as with certain adverse obstetrical and perinatal outcomes. If a fetal digit anomaly is suspected, a detailed assessment of fetal anatomy is mandatory to exclude other malformations. Springer-Verlag, 2009 Digital malformations nationallicence Polydactyly nationallicence Perinatal outcome nationallicence Cardiac malformations nationallicence Tzur Tamar Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut Sheiner Eyal Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut Weintraub Adi Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut Mazor Moshe Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut Wiznitzer Arnon Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut Silberstein Eldad Department of Plastic Surgery, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel aut Holcberg Gershon Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut Silberstein Tali Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut Archives of Gynecology and Obstetrics Springer-Verlag 283/1(2011-01-01), 47-52 0932-0067 283:1<47 2011 283 404 https://doi.org/10.1007/s00404-009-1275-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-009-1275-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tzur Tamar Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut NATIONALLICENCE 700 1- Sheiner Eyal Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut NATIONALLICENCE 700 1- Weintraub Adi Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut NATIONALLICENCE 700 1- Mazor Moshe Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut NATIONALLICENCE 700 1- Wiznitzer Arnon Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut NATIONALLICENCE 700 1- Silberstein Eldad Department of Plastic Surgery, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel aut NATIONALLICENCE 700 1- Holcberg Gershon Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut NATIONALLICENCE 700 1- Silberstein Tali Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/1(2011-01-01), 47-52 0932-0067 283:1<47 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer