caa a22 4500 445306351 CHVBK 20180317142614.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00404-009-1288-5 doi (NATIONALLICENCE)springer-10.1007/s00404-009-1288-5 Effect of pre-pregnancy body mass index on adverse pregnancy outcome in north of China [Elektronische Daten] [Xuemin Liu, Juan Du, Guixi Wang, Zhenyu Chen, Wei Wang, Qi Xi] Purpose: To investigate the effect of pre-pregnancy BMI on adverse maternal and neonatal outcomes in pregnancy women of northern China. Methods: We conducted a retrospective population-based cohort study of 5,047 singleton nulliparous pregnancies. The subjects were categorized into four groups by BMI-underweight (BMI<18.5kg/m2), normal (BMI 18.5-24kg/m2), overweight (BMI 24-28kg/m2) and obese (BMI≥28kg/m2). Logistic regression was used to adjust the potential confounder. Maternal and neonatal outcomes were evaluated with relative risks and 95% confidence intervals. Results: 11.5, 63.4, 18.3, and 6.8% of the subjects were underweight, normal BMI, overweight and obese, respectively. Compared with women of normal BMI, the risk of the following outcomes was significantly increased in overweight and obese women and expressed as [adjusted RR (95% confidence interval)] respectively: pre-eclampsia [2.99 (2.21-4.06), 5.68 (3.97-8.11)]; gestational diabetes [2.49 (1.82-3.39), 4.35 (3.00-6.31)]; premature rupture of the membranes [1.64 (1.20-2.23), 1.73 (1.11-2.72)]; abruption placentae [1.84 (1.19-2.87), 2.79 (1.60-4.83)]; cesarian section [1.47 (1.27-1.70), 2.51 (1.97-3.20)]; postpartum hemorrhage [2.31 (1.51-3.54), 3.73 (2.37-5.04)]; perineal rupture [2.89 (1.44-5.81), 3.36 (1.55-7.30)]; large-for-gestational age [1.46 (1.02-2.08), 1.91 (1.17-3.10)]. However, anemia (2.54, 1.15-5.63), small-for-gestational age (1.67, 1.07-2.61) were significantly more common in the underweight group. Conclusions: The prevalence of overweight and obesity in women of northern China is much lower than in the Caucasian population or Chinese in Hong Kong. The increased maternal BMI is associated with many adverse pregnancy outcomes and its risk increases with the degree of obesity. Maternal underweight has a protective effect although increases the risk of having small-for-gestational age baby and anemia. Springer-Verlag, 2009 Body mass index nationallicence Obesity nationallicence Pregnancy outcome nationallicence Chinese nationallicence Liu Xuemin Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut Du Juan Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut Wang Guixi Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut Chen Zhenyu Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut Wang Wei Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut Xi Qi Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut Archives of Gynecology and Obstetrics Springer-Verlag 283/1(2011-01-01), 65-70 0932-0067 283:1<65 2011 283 404 https://doi.org/10.1007/s00404-009-1288-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-009-1288-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Liu Xuemin Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut NATIONALLICENCE 700 1- Du Juan Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut NATIONALLICENCE 700 1- Wang Guixi Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut NATIONALLICENCE 700 1- Chen Zhenyu Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut NATIONALLICENCE 700 1- Wang Wei Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut NATIONALLICENCE 700 1- Xi Qi Department of Obsterics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/1(2011-01-01), 65-70 0932-0067 283:1<65 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer