caa a22 4500 445306394 CHVBK 20180317142614.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00404-010-1561-7 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1561-7 Misoprostol and termination of pregnancy: is there a need for ultrasound screening in a general population to assess the risk for adverse outcome in cases of uterine anomaly? [Elektronische Daten] [N. van der Veen, J. Brouns, J. Doornbos, W. van Wijngaarden] Purpose and methods: We reviewed the existing literature on medical termination of pregnancy in cases of congenital uterine malformation. Is medical termination of pregnancy safe in the presence of a uterine anomaly? Can termination of pregnancy still be performed when information concerning the presence of congenital uterine malformation is not available? Results: The risk of adverse outcome, i.e. uterine rupture, was high in class 2 uterine anomalies, whereas the risks in classes 3-6 were negligible. However, the very low incidence of class 2 anomalies in pregnant women results in a calculated risk of uterine rupture in medical termination of pregnancy on the basis of this anomaly of 1 in 300,000 pregnancies. Ultrasound scanning is of limited diagnostic value to diagnose congenital uterine malformations. Conclusions: The implications of uterine anomalies are not an argument in the discussion whether to use misoprostol for termination of pregnancy in developing countries with scarce diagnostics tools. The Author(s), 2010 Misoprostol nationallicence Uterine anomalies nationallicence Diagnostic ultrasound scanning safety nationallicence van der Veen N. Department of Obstetrics and Gynecology, Zaans Medical Centre, Julianaplein 58, 1502 DV, Zaandam, The Netherlands aut Brouns J. Department of Obstetrics and Gynecology, Zaans Medical Centre, Julianaplein 58, 1502 DV, Zaandam, The Netherlands aut Doornbos J. Department of Obstetrics and Gynecology, Zaans Medical Centre, Julianaplein 58, 1502 DV, Zaandam, The Netherlands aut van Wijngaarden W. Department of Obstetrics and Gynecology, Bronovo Hospital, Bronovolaan 5, 2597 AX, The Hague, The Netherlands aut Archives of Gynecology and Obstetrics Springer-Verlag 283/1(2011-01-01), 1-5 0932-0067 283:1<1 2011 283 404 https://doi.org/10.1007/s00404-010-1561-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1561-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- van der Veen N. Department of Obstetrics and Gynecology, Zaans Medical Centre, Julianaplein 58, 1502 DV, Zaandam, The Netherlands aut NATIONALLICENCE 700 1- Brouns J. Department of Obstetrics and Gynecology, Zaans Medical Centre, Julianaplein 58, 1502 DV, Zaandam, The Netherlands aut NATIONALLICENCE 700 1- Doornbos J. Department of Obstetrics and Gynecology, Zaans Medical Centre, Julianaplein 58, 1502 DV, Zaandam, The Netherlands aut NATIONALLICENCE 700 1- van Wijngaarden W. Department of Obstetrics and Gynecology, Bronovo Hospital, Bronovolaan 5, 2597 AX, The Hague, The Netherlands aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/1(2011-01-01), 1-5 0932-0067 283:1<1 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer