caa a22 4500 445306548 CHVBK 20180317142614.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00404-011-1877-y doi (NATIONALLICENCE)springer-10.1007/s00404-011-1877-y Sonkusare Shipra Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal University, 576104, Manipal, Karnataka, India aut The clinical management of hyperemesis gravidarum [Elektronische Daten] [Shipra Sonkusare] Hyperemesis gravidarum is a severe and disabling condition with potentially life-threatening complications. It is likely to have a multifactorial etiology which contributes to the difficulty in treatment. Treatment is supportive with correction of dehydration and electrolyte disturbance, antiemetic therapy, prevention and treatment of complications like Wernicke's encephalopathy, osmotic demyelination syndrome, thromboembolism, and good psychological support. There are abundant data on the safety of antihistamines, phenothiazines, and metoclopromide in early pregnancy and treatment should therefore not be withheld on the basis of teratogenicity concerns. Thiamine replacement is indicated in hyperemesis gravidarum to prevent development of Wernicke's encephalopathy. Springer-Verlag, 2011 Nausea and vomiting of pregnancy nationallicence Hyperemesis gravidarum nationallicence Morning sickness nationallicence Wernicke's encephalopathy nationallicence Antiemetics nationallicence Archives of Gynecology and Obstetrics Springer-Verlag 283/6(2011-06-01), 1183-1192 0932-0067 283:6<1183 2011 283 404 https://doi.org/10.1007/s00404-011-1877-y text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-1877-y text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Sonkusare Shipra Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal University, 576104, Manipal, Karnataka, India aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/6(2011-06-01), 1183-1192 0932-0067 283:6<1183 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer