caa a22 4500 445306599 CHVBK 20180317142615.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00404-010-1585-z doi (NATIONALLICENCE)springer-10.1007/s00404-010-1585-z Second primary cancers following borderline ovarian tumors [Elektronische Daten] [Muzaffer Sanci, Emre Gultekin, Basak Cingillioglu, Ozge Gultekin, Seyfettin Ozvural, Volkan Emirdar, Yusuf Yildirim] Background: Several studies have reported an increased risk of second primary cancers subsequent to invasive epithelial ovarian cancer. However, there is no adequate data regarding such risk in borderline ovarian tumors (BOTs). The aim of this study was to evaluate the risk of subsequent second primary cancers among women with BOTs. Methods: BOT patients treated in our center between December 1985 and April 2009 were retrospectively screened for developing second primary cancer during follow-up period. Results: There were 96 women diagnosed with BOT. Mean age at the time of diagnosis was 47±14.3, ranging from 19 to 79. Eighty-eight (91.6%) patients had stage I disease, two patients (2.1%) had stage II and six (6.2%) had stage III. Twenty-five (26.0%) patients received platinum-based adjuvant chemotherapy. Mean follow-up time was 96.5±442months (range: 9-280months). There were ten (10.4%) recurrences. Only one patient developed second primary cancer. Second primary cancer observed in this case was basal cell carsinoma of the eyelid, which was diagnosed 2years after primary disease. There were no patients with common women's cancers such as breast and colorectal cancers. Conclusions: These findings do not suggest increased risk of subsequent cancers in patients with BOT. However, population-based studies are needed for evaluating exact risk of developing second primary malignancies in women with BOTs. Springer-Verlag, 2010 Second primary cancers nationallicence Borderline ovarian tumors (BOTs) nationallicence Sanci Muzaffer Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut Gultekin Emre Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut Cingillioglu Basak Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut Gultekin Ozge Department of Statistics, Faculty of Science, Ege University, Bornova, Izmir, Turkey aut Ozvural Seyfettin Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut Emirdar Volkan Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut Yildirim Yusuf Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut Archives of Gynecology and Obstetrics Springer-Verlag 283/6(2011-06-01), 1391-1396 0932-0067 283:6<1391 2011 283 404 https://doi.org/10.1007/s00404-010-1585-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1585-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sanci Muzaffer Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut NATIONALLICENCE 700 1- Gultekin Emre Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut NATIONALLICENCE 700 1- Cingillioglu Basak Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut NATIONALLICENCE 700 1- Gultekin Ozge Department of Statistics, Faculty of Science, Ege University, Bornova, Izmir, Turkey aut NATIONALLICENCE 700 1- Ozvural Seyfettin Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut NATIONALLICENCE 700 1- Emirdar Volkan Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut NATIONALLICENCE 700 1- Yildirim Yusuf Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ege Gynecology and Maternity Training and Research Hospital, Yenisehir, Izmir, Turkey aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/6(2011-06-01), 1391-1396 0932-0067 283:6<1391 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer