caa a22 4500 445306688 CHVBK 20180317142615.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00404-011-1840-y doi (NATIONALLICENCE)springer-10.1007/s00404-011-1840-y Chorionic villus sampling and the risk of preeclamspia: a systematic review and meta-analysis [Elektronische Daten] [Ahmet Basaran, Mustafa Basaran, Betül Topatan] Objective: To perform systematic review and meta-analysis to evaluate the risk of preeclampsia after chorionic villus sampling (CVS). Data sources: A systematic search of PubMED and Web of Science from inception through August 2010, and bibliographies of review articles and eligible studies were performed. Methods of study selection: Six studies reported the risk of preeclampsia after CVS. All of the identified studies were retrospective and included in analysis. Tabulation, integration, and results: Reporting quality of the identified studies according to quality assessment scale for methodology in retrospective clinical reporting was moderate. Pooling was performed in two strata for control: (1) patients without any invasive prenatal diagnostic procedure served as control group: no significant difference was found in the odds ratio (OR) of preeclampsia (OR 0.79, 95% CI 0.38-1.64), severe preeclampsia (OR 0.49, 95% CI 0.04-5.78), gestational hypertension (OR 0.76, 95% CI 0.46-1.26), all pregnancy-induced hypertensive disorders (OR 0.80, 95% CI 0.46-1.41) between CVS and control groups. (2) Patients with amniocentesis combined with patients without any invasive prenatal diagnostic procedure served as control group: no significant difference was found in the OR of preeclampsia (OR 0.76, 95% CI 0.37-1.53), severe preeclampsia (OR 0.83, 95% CI 0.14-4.85), all pregnancy-induced hypertensive disorders (OR 0.92, 95% CI 0.55-1.53) between CVS and combined control groups. Conclusion: None of the included studies were randomized prospective trials designed to investigate the effect of CVS on preeclampsia. Accordingly, this review is limited by the heterogeneity, small number and retrospective nature of the available studies. CVS does not seem to increase the risk of preeclampsia or other pregnancy-induced hypertensive disorders. However, randomized prospective trials that are designed to investigate the risk of preeclampsia after CVS are needed to make a definite conclusion. Springer-Verlag, 2011 Preeclampsia nationallicence Chorionic villus sampling nationallicence Pregnancy nationallicence Systematic review nationallicence Meta-analysis nationallicence Gestational hypertension nationallicence Pregnancy induced hypertension nationallicence CVS : Chorionic villus sampling nationallicence OR : Odds ratio nationallicence CI : Confidence interval nationallicence Basaran Ahmet Department of Obstetrics and Gynecology, ACIBADEM Kayseri Hospital, Kayseri, Turkey aut Basaran Mustafa Department of Obstetrics and Gynecology, Konya Education and Research Hospital, Konya, Turkey aut Topatan Betül Department of Anesthesiology and Reanimation, School of Medicine, Başkent University, Konya, Turkey aut Archives of Gynecology and Obstetrics Springer-Verlag 283/6(2011-06-01), 1175-1181 0932-0067 283:6<1175 2011 283 404 https://doi.org/10.1007/s00404-011-1840-y text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-1840-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Basaran Ahmet Department of Obstetrics and Gynecology, ACIBADEM Kayseri Hospital, Kayseri, Turkey aut NATIONALLICENCE 700 1- Basaran Mustafa Department of Obstetrics and Gynecology, Konya Education and Research Hospital, Konya, Turkey aut NATIONALLICENCE 700 1- Topatan Betül Department of Anesthesiology and Reanimation, School of Medicine, Başkent University, Konya, Turkey aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/6(2011-06-01), 1175-1181 0932-0067 283:6<1175 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer