caa a22 4500 445307188 CHVBK 20180317142616.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s00404-010-1753-1 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1753-1 Zavalza-Gómez Ana Division of Research, Hospital of Obstetrics and Gynecology at Western Medical Center, Mexican Institute of Social Security, Josefa Ortiz de Domínguez # 3694, Int 2. Colonia Yáñez, 44770, Guadalajara, Jalisco, México aut Obesity and oxidative stress: a direct link to preeclampsia? [Elektronische Daten] [Ana Zavalza-Gómez] Overweight is associated with alterations in lipid concentrations and an activation of inflammatory markers and both of these metabolic abnormalities are characteristic of preeclamptic pregnancies before the onset of clinically evident disease. Reactive oxygen species, particularly superoxide anions, evoke endothelial cell activation through many pathways. Markers of lipid peroxidation, including malondialdehyde and 8-epiprostaglandin-F2α, is increased in the plasma of women with preeclampsia, and the low concentrations of water- and lipid-soluble antioxidants in the plasma and the placenta further suggest a state of oxidative stress. This review focuses in the relation between maternal obesity, oxidative stress with development of preeclampsia. Springer-Verlag, 2010 Obesity nationallicence Oxidative stress nationallicence Preeclampsia nationallicence Archives of Gynecology and Obstetrics Springer-Verlag 283/3(2011-03-01), 415-422 0932-0067 283:3<415 2011 283 404 https://doi.org/10.1007/s00404-010-1753-1 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1753-1 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Zavalza-Gómez Ana Division of Research, Hospital of Obstetrics and Gynecology at Western Medical Center, Mexican Institute of Social Security, Josefa Ortiz de Domínguez # 3694, Int 2. Colonia Yáñez, 44770, Guadalajara, Jalisco, México aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/3(2011-03-01), 415-422 0932-0067 283:3<415 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer