caa a22 4500 445307390 CHVBK 20180317142617.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s00404-011-1894-x doi (NATIONALLICENCE)springer-10.1007/s00404-011-1894-x Maternal plasma and amniotic fluid coenzyme Q10 levels in preterm and term gestations: a pilot study [Elektronische Daten] [Enrique Terán, Marcia Racines-Orbe, Jorge Toapanta, Linda Valdivieso, Zulema Vega, Sandra Vivero, Walter Moya, Peter Chedraui, Faustino Pérez-López] Objective: To measure maternal plasma and amniotic fluid coenzyme Q10 (CoQ10) levels in preterm and term gestations. Study design: This pilot study comprised a convenience sample of 72 women admitted for labor with singleton live gestations and intact membranes (preterm n=27 and term n=45). Results: Median [interquartile range] maternal plasma CoQ10 levels did not differ among the studied women (preterm, 0.47 [0.12] vs. term, 0.47 [0.23] mmol/L, p=0.90). Overall CoQ10 amniotic fluid levels were nearly tenfold lower than those found in maternal plasma, with a significant lower level observed among those delivering preterm (0.050 [0.05] vs. 0.062 [0.04] mmol/L, p=0.007). Multiple linear regression analysis controlling for several covariates determined a significant correlation between amniotic fluid CoQ10 levels and neonatal gestational age. Conclusion: This is the first study to assess CoQ10 levels in amniotic fluid during pregnancy in which levels were significantly lower among those delivering preterm. More research is warranted in this regard. Springer-Verlag, 2011 Amniotic fluid nationallicence Antioxidant nationallicence Coenzyme Q10 nationallicence Preterm delivery nationallicence Ubiquinone nationallicence Terán Enrique Centro de Biomedicina, Universidad Central del Ecuador, Quito, Ecuador aut Racines-Orbe Marcia Centro de Biomedicina, Universidad Central del Ecuador, Quito, Ecuador aut Toapanta Jorge Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador aut Valdivieso Linda Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador aut Vega Zulema Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador aut Vivero Sandra Centro de Biomedicina, Universidad Central del Ecuador, Quito, Ecuador aut Moya Walter Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador aut Chedraui Peter Instituto de Biomedicina, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador aut Pérez-López Faustino Departamento de Obstetricia y Ginecología, Hospital Clínico de Zaragoza, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain aut Archives of Gynecology and Obstetrics Springer-Verlag 283(2011-03-01), 67-71 0932-0067 283<67 2011 283 404 https://doi.org/10.1007/s00404-011-1894-x text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-1894-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Terán Enrique Centro de Biomedicina, Universidad Central del Ecuador, Quito, Ecuador aut NATIONALLICENCE 700 1- Racines-Orbe Marcia Centro de Biomedicina, Universidad Central del Ecuador, Quito, Ecuador aut NATIONALLICENCE 700 1- Toapanta Jorge Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador aut NATIONALLICENCE 700 1- Valdivieso Linda Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador aut NATIONALLICENCE 700 1- Vega Zulema Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador aut NATIONALLICENCE 700 1- Vivero Sandra Centro de Biomedicina, Universidad Central del Ecuador, Quito, Ecuador aut NATIONALLICENCE 700 1- Moya Walter Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador aut NATIONALLICENCE 700 1- Chedraui Peter Instituto de Biomedicina, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador aut NATIONALLICENCE 700 1- Pérez-López Faustino Departamento de Obstetricia y Ginecología, Hospital Clínico de Zaragoza, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283(2011-03-01), 67-71 0932-0067 283<67 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer