caa a22 4500 445307439 CHVBK 20180317142617.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s00404-011-1855-4 doi (NATIONALLICENCE)springer-10.1007/s00404-011-1855-4 Paclitaxel and cisplatin chemotherapy for ovarian cancer during pregnancy: case report and review of the literature [Elektronische Daten] [Krystyna Serkies, Ewa Węgrzynowicz, Jacek Jassem] The safety of chemotherapy during pregnancy is debatable. We present a case of advanced ovarian cancer, diagnosed at week 28 of gestational age, treated with 2 cycles of paclitaxel/cisplatin (TC) chemotherapy during pregnancy, with no serious toxicity. At week 34, the patient underwent a caesarean section and delivered a healthy girl. Four additional cycles of TC were administered. Three months after completing chemotherapy, the patient developed abdominal progression and subsequently a huge metastatic cystic mass in the brain. Despite subsequent therapies, the patient died of progressive disease 35months after the diagnosis. The infant had normal growth and development by 73months of her age. This is another reported case of ovarian cancer diagnosed during the second trimester of the pregnancy treated with TC chemotherapy without apparent teratogenic effect. The Author(s), 2011 Pregnancy nationallicence Ovarian carcinoma nationallicence Chemotherapy nationallicence Serkies Krystyna Department of Oncology and Radiotherapy, Medical University of Gdańsk, 7 Dębinki St., 80-211, Gdańsk, Poland aut Węgrzynowicz Ewa Department of Oncology and Radiotherapy, Medical University of Gdańsk, 7 Dębinki St., 80-211, Gdańsk, Poland aut Jassem Jacek Department of Oncology and Radiotherapy, Medical University of Gdańsk, 7 Dębinki St., 80-211, Gdańsk, Poland aut Archives of Gynecology and Obstetrics Springer-Verlag 283(2011-03-01), 97-100 0932-0067 283<97 2011 283 404 https://doi.org/10.1007/s00404-011-1855-4 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-1855-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Serkies Krystyna Department of Oncology and Radiotherapy, Medical University of Gdańsk, 7 Dębinki St., 80-211, Gdańsk, Poland aut NATIONALLICENCE 700 1- Węgrzynowicz Ewa Department of Oncology and Radiotherapy, Medical University of Gdańsk, 7 Dębinki St., 80-211, Gdańsk, Poland aut NATIONALLICENCE 700 1- Jassem Jacek Department of Oncology and Radiotherapy, Medical University of Gdańsk, 7 Dębinki St., 80-211, Gdańsk, Poland aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283(2011-03-01), 97-100 0932-0067 283<97 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer