caa a22 4500 445307706 CHVBK 20180317142618.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s00404-010-1699-3 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1699-3 Secondary malignant fibrous histiocytoma of thigh with surface ulceration following radiotherapy for carcinoma cervix [Elektronische Daten] [Prerna Arora, Rachna Wadhwa, Nita Khurana, Shyama Jain, N. Hadke] Introduction: Radiotherapy is known to cause rarely various malignancies including leukemia, sarcoma, and thyroid and lung carcinoma. Post-radiation sarcomas account for 0.5-5.5% of all sarcomas; and include extra skeletal osteosarcoma, fibrosarcoma leiomyosarcoma, and malignant fibrous histiocytoma. Reports on post radiotherapy malignant fibrous histiocytoma in cervical cancer patients are rare. Case report: We present a case of 45-years-old female diagnosed with squamous cell carcinoma of the uterine cervix stage IIB; she underwent a radical hysterectomy with pelvic lymphadenectomy and postoperative radiotherapy and chemotherapy. Five years later, she presented with ulcerated nodular masses in right and left medial aspect of thigh. Cytological and histological diagnosis of the masses was malignant fibrous histiocytoma which was further confirmed by immunohistochemistry. Conclusion: Post-irradiation sarcoma must be considered in patients of carcinoma cervix treated with radiotherapy, when soft tissue mass is seen in the previously irradiated area. It should be differentiated from metastasis from primary tumor with the help of appropriate markers as it has a grave prognosis. Springer-Verlag, 2010 Cervical cancer nationallicence Post-irradiation tumors nationallicence Malignant fibrous histiocytoma nationallicence Skin ulceration nationallicence Arora Prerna Department of Pathology, Maulana Azad Medical College and Associated Hospitals, 110003, New Delhi, India aut Wadhwa Rachna Department of Pathology, Maulana Azad Medical College and Associated Hospitals, 110003, New Delhi, India aut Khurana Nita Department of Pathology, Maulana Azad Medical College and Associated Hospitals, 110003, New Delhi, India aut Jain Shyama Department of Pathology, Maulana Azad Medical College and Associated Hospitals, 20/59, Lodhi Colony, 110003, New Delhi, India aut Hadke N. Department of Surgery, Maulana Azad Medical College and Associated Hospitals, New Delhi, India aut Archives of Gynecology and Obstetrics Springer-Verlag 283(2011-03-01), 79-82 0932-0067 283<79 2011 283 404 https://doi.org/10.1007/s00404-010-1699-3 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1699-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Arora Prerna Department of Pathology, Maulana Azad Medical College and Associated Hospitals, 110003, New Delhi, India aut NATIONALLICENCE 700 1- Wadhwa Rachna Department of Pathology, Maulana Azad Medical College and Associated Hospitals, 110003, New Delhi, India aut NATIONALLICENCE 700 1- Khurana Nita Department of Pathology, Maulana Azad Medical College and Associated Hospitals, 110003, New Delhi, India aut NATIONALLICENCE 700 1- Jain Shyama Department of Pathology, Maulana Azad Medical College and Associated Hospitals, 20/59, Lodhi Colony, 110003, New Delhi, India aut NATIONALLICENCE 700 1- Hadke N. Department of Surgery, Maulana Azad Medical College and Associated Hospitals, New Delhi, India aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283(2011-03-01), 79-82 0932-0067 283<79 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer