caa a22 4500 44530782X CHVBK 20180317142618.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00404-010-1443-z doi (NATIONALLICENCE)springer-10.1007/s00404-010-1443-z Human papillomavirus genotypes distribution in cervical samples from women living with human immunodeficiency virus [Elektronische Daten] [Fabiana Melgaço, Maria Rosa, Everton Augusto, Jacqueline Haimuri, Claudia Jacintho, Larissa Santos, Silvia Cavalcanti, Ledy Oliveira] Background: The aim of this study was to determine the prevalence and relationship of human papillomavirus (HPV) genotypes in cervical samples from 140 human immunodeficiency virus (HIV)-seropositive women routinely attending an outpatient public gynecological service in the state of Rio de Janeiro, Brazil. Methods: MY09/11 consensus primers were used to detect generic HPV DNA. HPV typification was performed by restriction fragment length polymorphism analysis following polymerase chain reaction amplification. Results: The overall HPV prevalence was 60.0%. The identification of 24 different HPV genotypes including uncommon types was performed. A9 oncogenic genotypes were present in 54.02% of HIV-positive women. Abnormal cervical lesions, the time since HIV diagnosis and the number of sexual partners contributed independently to the high oncogenic HPV prevalence. The oncogenic and non-oncogenic group were similarly affected by risk factors in contrast to negative HPV women. The frequency of multiple infections was 20%; furthermore, all of them presented at least one oncogenic type. Conclusion: The analyzed sample represents an epidemiological source of uncommon infection. Due to high HPV prevalence, more frequent cytological screening and/or liberal colposcopic evaluations should be performed in HIV-positive patients. Springer-Verlag, 2010 Human papillomavirus nationallicence Human immunodeficiency virus nationallicence Restriction fragment length polymorphism nationallicence Cohort study nationallicence Melgaço Fabiana Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut Rosa Maria Department of Epidemiology and Biostatistics, Universidade Federal Fluminense, Niterói, RJ, Brazil aut Augusto Everton Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut Haimuri Jacqueline Hospital dos Servidores de Estado, Rio de Janeiro, RJ, Brazil aut Jacintho Claudia Hospital dos Servidores de Estado, Rio de Janeiro, RJ, Brazil aut Santos Larissa Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut Cavalcanti Silvia Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut Oliveira Ledy Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut Archives of Gynecology and Obstetrics Springer-Verlag 283/4(2011-04-01), 809-817 0932-0067 283:4<809 2011 283 404 https://doi.org/10.1007/s00404-010-1443-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1443-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Melgaço Fabiana Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut NATIONALLICENCE 700 1- Rosa Maria Department of Epidemiology and Biostatistics, Universidade Federal Fluminense, Niterói, RJ, Brazil aut NATIONALLICENCE 700 1- Augusto Everton Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut NATIONALLICENCE 700 1- Haimuri Jacqueline Hospital dos Servidores de Estado, Rio de Janeiro, RJ, Brazil aut NATIONALLICENCE 700 1- Jacintho Claudia Hospital dos Servidores de Estado, Rio de Janeiro, RJ, Brazil aut NATIONALLICENCE 700 1- Santos Larissa Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut NATIONALLICENCE 700 1- Cavalcanti Silvia Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut NATIONALLICENCE 700 1- Oliveira Ledy Department of Microbiology and Parasitology, Universidade Federal Fluminense, Rua Prof. Ernani Melo 101, 24210-130, Niterói, RJ, Brazil aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/4(2011-04-01), 809-817 0932-0067 283:4<809 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer