caa a22 4500 445307994 CHVBK 20180317142619.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00404-010-1426-0 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1426-0 Causes and consequences of 93 fetuses with cardiomegaly in a tertiary center in Thailand [Elektronische Daten] [Piyawadee Wuttikonsammakit, Boonchai Uerpairojkit, Somchai Tanawattanacharoen] Objectives: To assess etiology, perinatal mortality and associated factors of fetal cardiomegaly (FC). Methods: A retrospective study of fetuses with cardiomegaly was conducted. Demographic data, ultrasonographic findings, and outcomes were collected and analyzed. Results: Ninety-three fetuses were analyzed. The causes of FC were cardiac causes 49.5%, Bart's hemoglobinopathies 28%, and non-Bart's anemia 15%. Ascites, pericardial effusion, and hydrops were more prevalent in fetuses with anemia than those with cardiac abnormalities. The overall perinatal mortality was 69.9%. Although all Bart's hydrops died, perinatal mortality of non-Bart's anemia, and structural cardiac defect were 57.1 and 69.7%, respectively. Excluding Bart's anemia, receiver-operating characteristic curve analysis demonstrated that cardiothoracic ratio of ≥0.58 best predictive for perinatal mortality. Earlier gestational age at diagnosis, skin edema, and chromosomal abnormality were associated with higher mortality. Conclusions: Majority causes of FC were cardiac and anemic in origin. It carried high-perinatal mortality depending on the causes. Springer-Verlag, 2010 Echocardiography nationallicence Fetal anemia nationallicence Fetal cardiomegaly nationallicence Perinatal mortality nationallicence Ultrasound nationallicence Wuttikonsammakit Piyawadee Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, 10330, Bangkok, Thailand aut Uerpairojkit Boonchai Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, 10330, Bangkok, Thailand aut Tanawattanacharoen Somchai Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, 10330, Bangkok, Thailand aut Archives of Gynecology and Obstetrics Springer-Verlag 283/4(2011-04-01), 701-706 0932-0067 283:4<701 2011 283 404 https://doi.org/10.1007/s00404-010-1426-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1426-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wuttikonsammakit Piyawadee Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, 10330, Bangkok, Thailand aut NATIONALLICENCE 700 1- Uerpairojkit Boonchai Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, 10330, Bangkok, Thailand aut NATIONALLICENCE 700 1- Tanawattanacharoen Somchai Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, 10330, Bangkok, Thailand aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/4(2011-04-01), 701-706 0932-0067 283:4<701 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer