caa a22 4500 44530801X CHVBK 20180317142619.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00404-010-1716-6 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1716-6 Epithelioid cotyledonoid dissecting leiomyoma: a case report and review of the literature [Elektronische Daten] [Hooman Soleymani Majd, Lamiese Ismail, Shaila Desai, Philip Reginald] A 63-year-old mother of two, presented with blood-stained vaginal discharge and right sided lower abdominal pain. A MRI examination confirmed a right parametrial mass, abutting the lateral margin of the uterus and the patient had a total abdominal hysterectomy and bilateral salpingo-oophorectomy. Histological examination diagnosed a cotyledonoid leiomyoma, but with a new epithelioid variant. Cotyledonoid leiomyom's usually have a large, fungating appearance and demonstrate apparent widespread infiltrative growth and extension into the pelvic cavity, broad ligament and retroperitoneal space which may raise significant concern about the possibility of a malignant neoplasm. As these tumours are rare and infrequently encountered, it is imperative that clinicians be aware of this entity as they may pose a significant diagnostic and management challenge when encountered. Awareness of this newly described epithelioid cell variant of cotyledonoid dissecting leiomyoma is necessary for an accurate diagnosis and to facilitate appropriate management decisions at the time of surgery. This new variant further emphasizes the need for meticulous histopathological assessment which should be undertaken to circumvent misdiagnosis. This has direct clinical relevance to all operating gynaecologists and may have implications for litigation because patients may be inappropriately and inadvertently over-treated for an essentially benign condition. Springer-Verlag, 2010 Leiomyoma nationallicence Cotyledonoid nationallicence Dissecting nationallicence Epithelioid variant nationallicence Broad ligament nationallicence Malignancy nationallicence Soleymani Majd Hooman Department of Obstetrics and Gynaecology, Stoke Mandeville Hospital, Mandeville Road, HP21 8AL, Aylesbury, UK aut Ismail Lamiese Department of Obstetrics and Gynaecology, Stoke Mandeville Hospital, Mandeville Road, HP21 8AL, Aylesbury, UK aut Desai Shaila Department of Histopathology, West Middlesex University Hospital, Twickenham Road, Isleworth, TW7 6AF, Middlesex, UK aut Reginald Philip Department of Obstetrics and Gynaecology, Wexham Park Hospital, Wexham Street, Slough, SL2 4HL, Berkshire, UK aut Archives of Gynecology and Obstetrics Springer-Verlag 283/4(2011-04-01), 771-774 0932-0067 283:4<771 2011 283 404 https://doi.org/10.1007/s00404-010-1716-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1716-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Soleymani Majd Hooman Department of Obstetrics and Gynaecology, Stoke Mandeville Hospital, Mandeville Road, HP21 8AL, Aylesbury, UK aut NATIONALLICENCE 700 1- Ismail Lamiese Department of Obstetrics and Gynaecology, Stoke Mandeville Hospital, Mandeville Road, HP21 8AL, Aylesbury, UK aut NATIONALLICENCE 700 1- Desai Shaila Department of Histopathology, West Middlesex University Hospital, Twickenham Road, Isleworth, TW7 6AF, Middlesex, UK aut NATIONALLICENCE 700 1- Reginald Philip Department of Obstetrics and Gynaecology, Wexham Park Hospital, Wexham Street, Slough, SL2 4HL, Berkshire, UK aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/4(2011-04-01), 771-774 0932-0067 283:4<771 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer