caa a22 4500 445308273 CHVBK 20180317142620.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00404-010-1480-7 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1480-7 An analysis of HELLP syndrome cases: does platelet count predict adverse maternal and fetal outcomes in women with HELLP syndrome? [Elektronische Daten] [Gulseren Yucesoy, Yigit Cakiroglu, Harika Bodur, Sebiha Ozkan, Temel Tan] Purpose: To evaluate the maternal and fetal outcome in 44 pregnancies complicated with HELLP syndrome and to investigate the role of platelet counts in its prognosis. Methods: A retrospective analysis of the medical records of 44 patients with the diagnosis of hemolysis elevated liver enzymes and low platelet count between June 1997 and January 2009 was performed. The patients were divided into two groups according to blood platelet count: platelet count <50,000mm3 formed Group I and platelet count 50,000-100,000mm3 formed Group II. Clinical findings and laboratory characteristics, maternal complications, perinatal outcomes and comparison of maternal and fetal morbidity according to platelet counts were analyzed. Results: During the period of 12years, 44 (0.54%) of 8,132 deliveries had HELLP syndrome. Among 44 patients, the most common complications were disseminated intravascular coagulopathy (18.2%), acute renal failure (15.9%), abruptio placentae (11.4%), and cerebral hemorrhage/infarction (11.4%). Maternal and perinatal mortality rates in HELLP syndrome were 9.1 and 40.9%, respectively. Aspartate aminotransferase levels were found to be statistically significantly higher in Group I (p=0.04). While disseminated intravascular coagulopathy and acute renal failure were statistically significantly higher in Group I (p=0.01; p=0.03 respectively), fetal growth restriction was statistically significantly higher in Group II (p=0.04). Conclusions: HELLP syndrome is associated with high incidences of maternal and fetal morbidity and mortality and patients with low platelet counts might have a much increased risk. Springer-Verlag, 2010 HELLP syndrome nationallicence Platelet count nationallicence Complication nationallicence Prognosis nationallicence Yucesoy Gulseren Obstetrics and Gynecology Department, Kocaeli University Faculty of Medicine, Kocaeli, Turkey aut Cakiroglu Yigit Obstetrics and Gynecology Department, Kocaeli University Faculty of Medicine, Kocaeli, Turkey aut Bodur Harika Obstetrics and Gynecology Department, Acibadem University, Istanbul, Turkey aut Ozkan Sebiha Obstetrics and Gynecology Department, Kocaeli University Faculty of Medicine, Kocaeli, Turkey aut Tan Temel Obstetrics and Gynecology Department, Kocaeli University Faculty of Medicine, Kocaeli, Turkey aut Archives of Gynecology and Obstetrics Springer-Verlag 283/5(2011-05-01), 941-945 0932-0067 283:5<941 2011 283 404 https://doi.org/10.1007/s00404-010-1480-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1480-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yucesoy Gulseren Obstetrics and Gynecology Department, Kocaeli University Faculty of Medicine, Kocaeli, Turkey aut NATIONALLICENCE 700 1- Cakiroglu Yigit Obstetrics and Gynecology Department, Kocaeli University Faculty of Medicine, Kocaeli, Turkey aut NATIONALLICENCE 700 1- Bodur Harika Obstetrics and Gynecology Department, Acibadem University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Ozkan Sebiha Obstetrics and Gynecology Department, Kocaeli University Faculty of Medicine, Kocaeli, Turkey aut NATIONALLICENCE 700 1- Tan Temel Obstetrics and Gynecology Department, Kocaeli University Faculty of Medicine, Kocaeli, Turkey aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/5(2011-05-01), 941-945 0932-0067 283:5<941 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer