caa a22 4500 445308370 CHVBK 20180317142620.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00404-010-1505-2 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1505-2 The value of urocortin and Ca-125 in the diagnosis of endometrioma [Elektronische Daten] [Aytekin Tokmak, Mustafa Ugur, Esra Tonguc, Turgut Var, Ozlem Moraloğlu, Gülnur Ozaksit] Purposes: In this study, we sought to establish the value of a new molecule, urocortin (Ucn), in the diagnosis of endometrioma and compare with Ca-125 to identify superiority of urocortin. Methods: Of the patients operated on at our hospital with the initial diagnosis of adnexal mass, 88 patients whose pathology results were endometrioma and benign ovarian cyst were included in the study. As a result of the pathological examination, the patients were assessed in two groups. Group 1 consisted of 42 cases of endometrioma and Group 2 included 46 cases of benign ovarian cyst (control group). The serum Ucn and CA 125 levels of patients were measured from the blood samples drawn prior to the operation. Results: While the serum Ucn level was 4.8±1.00ng/ml in the endometrioma group, it was 4.5±1.03ng/ml in the control group (P=0.21). The difference was statistically not meaningful. On the other hand, mean serum Ca-125 level was 43.8U/l (11.7-251) in the endometrioma group, it was 16.5U/l (4.3-121.1) in the control group. The difference was statistically meaningful (P=0.001). When the cut-off point for Serum Ca-125 level was taken as 21.38, sensitivity and specificity levels were found to be 88.1 and 63%. When the cut-off point for Ucn was taken as 4.16, sensitivity was 76.2%, and specificity 45.7%. Conclusion: Ucn was not found to be efficient in distinguishing endometrioma from other benign ovarian cysts or to be superior to CA125 in the diagnosis of endometrioma. Springer-Verlag, 2010 Endometrioma nationallicence Benign ovarian cyst nationallicence Urocortin nationallicence Ca-125 nationallicence Tokmak Aytekin Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut Ugur Mustafa Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut Tonguc Esra Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut Var Turgut Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut Moraloğlu Ozlem Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut Ozaksit Gülnur Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut Archives of Gynecology and Obstetrics Springer-Verlag 283/5(2011-05-01), 1075-1079 0932-0067 283:5<1075 2011 283 404 https://doi.org/10.1007/s00404-010-1505-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1505-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tokmak Aytekin Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Ugur Mustafa Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Tonguc Esra Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Var Turgut Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Moraloğlu Ozlem Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Ozaksit Gülnur Department of Reproductive Endocrinology, Zekai Tahir Burak Women's Health Research and Education Hospital, Tunali Hilmi Cad. Binnaz Sok. No:1/5 Kavaklidere, 06100, Ankara, Turkey aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/5(2011-05-01), 1075-1079 0932-0067 283:5<1075 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer