caa a22 4500 445308435 CHVBK 20180317142620.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00404-010-1568-0 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1568-0 Impact of positron emission tomography/computed tomography in the management of patients with epithelial ovarian carcinoma after treatment [Elektronische Daten] [Kaei Nasu, Wakana Abe, Noriyuki Takai, Kenichiro Tomonari, Hisashi Narahara] Purpose: The aims of this study were to compare the usefulness and reliability of integrated whole-body positron emission tomography/computed tomography (PET/CT) using 18F-fluorodeoxyglucose (FDG) with those of contrast-enhanced multidetector CT during regular follow-up in patients after initial treatment of ovarian cancer, to assess the impact of FDG-PET/CT on the confirmation of recurrence, restaging, and clinical management of patients, and to determine the incremental information provided by PET/CT. Methods: A retrospective review was performed on 19 ovarian cancer patients who underwent a total of 30 FDG-PET/CT and contrast-enhanced multidetector CT scans. The following information was obtained: the clinical information of the patients; the results of FDG-PET/CT and contrast-enhanced multidetector CT, particularly with regard to the impact on the diagnosis of recurrence; information on the localization and number of diseases; and the impact on subsequent clinical management. Results: Both FDG-PET/CT and contrast-enhanced multidetector CT had very high sensitivity and specificity for the detection of recurrent ovarian cancer. Contrast-enhanced multidetector CT was considered the more accurate imaging modality for detecting recurrence, whereas FDG-PET/CT was proven more effective for detecting large numbers of small lesions. When comparing the impact on the choice of a management plan, both FDG-PET/CT and contrast-enhanced multidetector CT were found to be significantly effective at predicting the locations of recurrence. Conclusions: Both integrated FDG-PET/CT and contrast-enhanced multidetector CT are sensitive surveillance modalities for the detection of recurrent ovarian cancer; the use of both modalities aids decisions on treatment plans and may ultimately have a favorable impact on prognosis. However, contrast-enhanced multidetector CT is recommended for the regular follow-up for ovarian cancer patients after initial treatment. Springer-Verlag, 2010 Epithelial ovarian cancer nationallicence Recurrence nationallicence FDG-PET/CT nationallicence Contrast-enhanced CT nationallicence Secondary cytoreductive surgery nationallicence Second-line chemotherapy nationallicence Nasu Kaei Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama-machi, Yufu, 879-5593, Oita, Japan aut Abe Wakana Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama-machi, Yufu, 879-5593, Oita, Japan aut Takai Noriyuki Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama-machi, Yufu, 879-5593, Oita, Japan aut Tomonari Kenichiro Oita Diagnostic Imaging Center, Oita, Japan aut Narahara Hisashi Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama-machi, Yufu, 879-5593, Oita, Japan aut Archives of Gynecology and Obstetrics Springer-Verlag 283/5(2011-05-01), 1121-1126 0932-0067 283:5<1121 2011 283 404 https://doi.org/10.1007/s00404-010-1568-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1568-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nasu Kaei Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama-machi, Yufu, 879-5593, Oita, Japan aut NATIONALLICENCE 700 1- Abe Wakana Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama-machi, Yufu, 879-5593, Oita, Japan aut NATIONALLICENCE 700 1- Takai Noriyuki Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama-machi, Yufu, 879-5593, Oita, Japan aut NATIONALLICENCE 700 1- Tomonari Kenichiro Oita Diagnostic Imaging Center, Oita, Japan aut NATIONALLICENCE 700 1- Narahara Hisashi Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Idaigaoka 1-1, Hasama-machi, Yufu, 879-5593, Oita, Japan aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/5(2011-05-01), 1121-1126 0932-0067 283:5<1121 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer