caa a22 4500 445308648 CHVBK 20180317142621.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00404-010-1706-8 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1706-8 Matevosyan Naira Open Medical Institute, Salzburg Stiftung, Austria aut Pregnancy and postpartum specifics in women with schizophrenia: a meta-study [Elektronische Daten] [Naira Matevosyan] Objective: This meta-study intends to elucidate schizophrenia-pregnancy inferences. Methods: A total of 63 quasi-randomized, case-control, linkage studies on outcomes of singleton pregnancies in women with schizophrenia are identified through PubMed, ACOG, and SCOPUS. A sample of 216 pregnant and puerperal women with schizophrenia, allocated from studies of level I-IIA evidence, is compared with a sample of 487 births to unaffected women. Calculations use births as unit of analysis. Poisson regression model is used in exchangeable correlation structure. Results: Older age (2.13), excessive smoking (1.85) and less antenatal care (1.92) in women with schizophrenia determine high risk for prematurity (2.08), including miscarriages (2.04) and preterm birth (1.98). Neonates to mothers with schizophrenia are profiled with twice likelihood of low Apgar scores (2.22), intrauterine growth retardation (2.16), and congenital defects (2.1). Poor maternal-fetal attachment and preoccupation about fetus are related to negative symptoms of schizophrenia (−0.518), length of antipsychotic treatment (−0.304) and are not associated with maternal age (0.216). Postpartum period is eventful with psychotic relapse (7.86), and parenting difficulties (11.2). Conclusions: After adjusting for age, parity, unhealthy behaviors, length of antipsychotic treatment, and maternal-fetal attachment, maternal schizophrenia remains predictive to prematurity and postpartum psychosis. Springer-Verlag, 2010 Maternal schizophrenia nationallicence Maternal-fetal attachment nationallicence Perinatal outcomes nationallicence Archives of Gynecology and Obstetrics Springer-Verlag 283/2(2011-02-01), 141-147 0932-0067 283:2<141 2011 283 404 https://doi.org/10.1007/s00404-010-1706-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1706-8 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Matevosyan Naira Open Medical Institute, Salzburg Stiftung, Austria aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/2(2011-02-01), 141-147 0932-0067 283:2<141 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer