caa a22 4500 445308753 CHVBK 20180317142622.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00404-010-1601-3 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1601-3 Clinical evaluation of women with PMB. Is it always necessary an endometrial biopsy to be performed? A review of the literature [Elektronische Daten] [Marina Dimitraki, Panagiotis Tsikouras, Sophia Bouchlariotou, Alexandros Dafopoulos, Vasileios Liberis, Georgios Maroulis, Alexander Teichmann] Background: Endometrial carcinoma is the most distressing cause of abnormal vaginal bleeding. The intention of clinical management in the case of postmenopausal bleeding is to achieve an accurate diagnosis without overinvestigation. Method: We studied the available literature on the diagnostic evaluation of postmenopausal women with vaginal bleeding, accentuating the most important aspects on this topic: the accuracy of sonography and endometrial biopsy in predicting endometrial hyperplasia and endometrial carcinoma. Results: The accuracy of the above tests in predicting endometrial hyperplasia and endometrial carcinoma is a subject of continuing debate. Μοreover, in the last decades, there has been an explosion of publications indicating that ultrasound may be useful in predicting endometrial pathology. Conclusion: Since advanced endometrial carcinoma has been known to occur in cases without noticeable endometrial thickness on ultrasound, the clinician should beware of the diagnostic evaluation of postmenopausal women with vaginal bleeding. The Author(s), 2010 Postmenopausal bleeding nationallicence Endometrial thickness nationallicence Biopsy nationallicence Dimitraki Marina Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut Tsikouras Panagiotis Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut Bouchlariotou Sophia Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut Dafopoulos Alexandros Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut Liberis Vasileios Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut Maroulis Georgios Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut Teichmann Alexander Department of Obstetrics and Gynecology, Teaching Hospital of Aschaffenburg, Aschaffenburg, Germany aut Archives of Gynecology and Obstetrics Springer-Verlag 283/2(2011-02-01), 261-266 0932-0067 283:2<261 2011 283 404 https://doi.org/10.1007/s00404-010-1601-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1601-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dimitraki Marina Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut NATIONALLICENCE 700 1- Tsikouras Panagiotis Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut NATIONALLICENCE 700 1- Bouchlariotou Sophia Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut NATIONALLICENCE 700 1- Dafopoulos Alexandros Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut NATIONALLICENCE 700 1- Liberis Vasileios Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut NATIONALLICENCE 700 1- Maroulis Georgios Department of Obstetrics and Gynecology, University Hospital of Alexandroupolis, Democritus University of Thrace, 68100, Alexandroupolis, Greece aut NATIONALLICENCE 700 1- Teichmann Alexander Department of Obstetrics and Gynecology, Teaching Hospital of Aschaffenburg, Aschaffenburg, Germany aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/2(2011-02-01), 261-266 0932-0067 283:2<261 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer