caa a22 4500 445308818 CHVBK 20180317142622.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00404-009-1332-5 doi (NATIONALLICENCE)springer-10.1007/s00404-009-1332-5 Association of serum relaxin with striae gravidarum in pregnant women [Elektronische Daten] [Samuel Lurie, Zippora Matas, Asora Fux, Abraham Golan, Oscar Sadan] Aims: The cause of striae gravidarum is still unclear. The study objective was to test the hypothesis that relaxin is involved in the process of striae gravidarum appearance during pregnancy. Methods: A prospective observational study in 32 pregnant women. Participants were observed at 12th, 24th and 36th gestational week. During each session, striae scoring was assessed and blood for relaxin estimation was withdrawn. The striae assessment was done according to Davey score. Serum relaxin was estimated using Relaxin ELISA kit (Immunodiagnostic AG, Bensheim, Germany). Results: Serum relaxin levels decreased as the pregnancy advanced (585.9±295.1, 424.2±253.8, 402.1±221.2pg/ml, respectively) but this decrease did not attain statistical significance. Pregnant women with striae gravidarum had lower serum relaxin levels compared to those without striae gravidarum at 36th gestational weeks, 330.8±175.2 vs 493.8±245.8pg/ml (P=0.037), respectively. The severity of striae gravidarum during pregnancy did not correlate with serum relaxin levels. Conclusion: Lower serum relaxin levels could contribute to the occurrence of striae gravidarum during pregnancy through decreased elasticity of the connective tissue. Springer-Verlag, 2010 Relaxin nationallicence Striae gravidarum nationallicence Pregnancy nationallicence Lurie Samuel Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel aut Matas Zippora Department of Biochemistry, Edith Wolfson Medical Center, Holon, Israel aut Fux Asora Department of Biochemistry, Edith Wolfson Medical Center, Holon, Israel aut Golan Abraham Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel aut Sadan Oscar Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel aut Archives of Gynecology and Obstetrics Springer-Verlag 283/2(2011-02-01), 219-222 0932-0067 283:2<219 2011 283 404 https://doi.org/10.1007/s00404-009-1332-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-009-1332-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lurie Samuel Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel aut NATIONALLICENCE 700 1- Matas Zippora Department of Biochemistry, Edith Wolfson Medical Center, Holon, Israel aut NATIONALLICENCE 700 1- Fux Asora Department of Biochemistry, Edith Wolfson Medical Center, Holon, Israel aut NATIONALLICENCE 700 1- Golan Abraham Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel aut NATIONALLICENCE 700 1- Sadan Oscar Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/2(2011-02-01), 219-222 0932-0067 283:2<219 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer