caa a22 4500 445308907 CHVBK 20180317142622.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00404-010-1449-6 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1449-6 Unilateral tubal twin ectopic pregnancy treated with single-dose methotrexate [Elektronische Daten] [Deniz Arikan, Gurkan Kiran, Ayhan Coskun, Bulent Kostu] Background: Spontaneous tubal twin pregnancy is a rare condition with an incidence of 1 in every 125,000 pregnancies. We present the case of a unilateral tubal twin ectopic pregnancy treated with single-dose methotrexate. Case: A 26-year-old nulliparous woman was admitted to our clinic with a complaint of vaginal bleeding and leftside pelvic pain. Her serum β-human chorionic gonadotropin (β-hCG) level was 18,780 mIU/mL and ultrasound revealed tubal twin pregnancy of 7 weeks' gestation. Because her vital signs were stable and no sign of tubal rupture was present, we performed single-dose (100 mg) methotrexate intramuscularly. In the follow-up, serum β-hCG levels were found to be 7,600 mIU/ml on day 7, 948 mIU/ml on day 20, 126 mIU/ml on day 26 and <10 mIU/ml on day 42. Conclusion: Methotrexate theraphy may be preferred in tubal twin ectopic pregnancies when the vital signs of the patient are stable and the fetal cardiac activities are negative. Springer-Verlag, 2010 Infertility nationallicence Methotrexate nationallicence Tubal twin pregnancy nationallicence Arikan Deniz Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, Yörük Selim Mah. Gazi Mustafa Kuşçu Cad., 46050, Kahramanmaraş, Turkey aut Kiran Gurkan Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, Yörük Selim Mah. Gazi Mustafa Kuşçu Cad., 46050, Kahramanmaraş, Turkey aut Coskun Ayhan Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, Yörük Selim Mah. Gazi Mustafa Kuşçu Cad., 46050, Kahramanmaraş, Turkey aut Kostu Bulent Sereflikochisar State Hospital, Sereflikochisar, Ankara, Turkey aut Archives of Gynecology and Obstetrics Springer-Verlag 283/2(2011-02-01), 397-399 0932-0067 283:2<397 2011 283 404 https://doi.org/10.1007/s00404-010-1449-6 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1449-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Arikan Deniz Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, Yörük Selim Mah. Gazi Mustafa Kuşçu Cad., 46050, Kahramanmaraş, Turkey aut NATIONALLICENCE 700 1- Kiran Gurkan Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, Yörük Selim Mah. Gazi Mustafa Kuşçu Cad., 46050, Kahramanmaraş, Turkey aut NATIONALLICENCE 700 1- Coskun Ayhan Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, Yörük Selim Mah. Gazi Mustafa Kuşçu Cad., 46050, Kahramanmaraş, Turkey aut NATIONALLICENCE 700 1- Kostu Bulent Sereflikochisar State Hospital, Sereflikochisar, Ankara, Turkey aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 283/2(2011-02-01), 397-399 0932-0067 283:2<397 2011 283 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer