caa a22 4500 445309210 CHVBK 20180317142623.0 cr unu---uuuuu 170323e20110701xx s 000 0 eng 10.1007/s00404-010-1599-6 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1599-6 A comparison of the effect of short-term aromatase inhibitor (letrozole) and GnRH agonist (triptorelin) versus case control on pregnancy rate and symptom and sign recurrence after laparoscopic treatment of endometriosis [Elektronische Daten] [Saeed Alborzi, Bahareh Hamedi, Azizeh Omidvar, Sedigheh Dehbashi, Soroosh Alborzi, Mehrnoosh Alborzi] Purpose: To compare the role of an aromatase inhibitor (letrozole) with a GnRH agonist (triptorelin) versus case control on the pregnancy rate and recurrence of symptoms and signs in patients with endometriosis. Methods: In a prospective randomized clinical trial, after treatment of 144 infertile women in their reproductive age by laparoscopy (whose endometriosis was confirmed by prior laparoscopy), they were divided into 3 groups: group 1 (47 cases) who received letrozole for 2months, group 2 (40 patients) who were prescribed triptorelin for 2months and group 3 who were 57 patients in the control group and did not receive any medication. We followed up each group at least for 12months after their restoration of regular cycle. Results: Pregnancy rate was 23.4% in group 1, 27.5% in group 2, and 28.1% in group 3. The results did not show significant differences among the 3 groups. Recurrence rate of endometriosis was 6.4% in group 1, 5% group 2 and 5.3% in group 3, which was not statistically significantly different as well. Conclusion: Pregnancy rate and endometriosis recurrence rate are comparable among the 3 groups. Springer-Verlag, 2010 Letrozole nationallicence Triptorelin nationallicence Endometriosis nationallicence Laparoscopy nationallicence Alborzi Saeed Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut Hamedi Bahareh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut Omidvar Azizeh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut Dehbashi Sedigheh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut Alborzi Soroosh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut Alborzi Mehrnoosh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut Archives of Gynecology and Obstetrics Springer-Verlag 284/1(2011-07-01), 105-110 0932-0067 284:1<105 2011 284 404 https://doi.org/10.1007/s00404-010-1599-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1599-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Alborzi Saeed Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut NATIONALLICENCE 700 1- Hamedi Bahareh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut NATIONALLICENCE 700 1- Omidvar Azizeh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut NATIONALLICENCE 700 1- Dehbashi Sedigheh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut NATIONALLICENCE 700 1- Alborzi Soroosh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut NATIONALLICENCE 700 1- Alborzi Mehrnoosh Division of Infertility and Endoscopic Surgery, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, P.O. Box 71345-1818, Shiraz, Iran aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/1(2011-07-01), 105-110 0932-0067 284:1<105 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer