caa a22 4500 445309288 CHVBK 20180317142623.0 cr unu---uuuuu 170323e20110701xx s 000 0 eng 10.1007/s00404-010-1590-2 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1590-2 Randomized trial of oral versus sublingual misoprostol 24h after mifepristone for medical abortion [Elektronische Daten] [Krishna Dahiya, Sonika Mann, Smiti Nanda] Objectives: To assess the efficacy, side effects, and acceptability of medical abortion using oral mifepristone (200mg) followed 24h later by oral or sublingual misoprostol (400μg). Materials and methods: A total of 93 women with pregnancies up to 56days of gestational age were assigned to two groups according to the different misoprostol regimen (group I 400μg orally and group II 400μg sublingually). The principle outcome measure was complete abortion defined as a complete expulsion of intrauterine contents without a need for surgical intervention 7days after the procedure. Results: Successful abortion occurred in 87.5% of patients in group 1 and 95.5% patients in group 2 (p=0.166, 95% CI −0.194, 0.033). The patient acceptability and satisfaction rates were similar in both the groups. Conclusion: It is concluded that 400μg of sublingual misoprostol is as effective as oral misoprostol 24h after mifepristone for medical abortion of ≤56days. Springer-Verlag, 2010 Sublingual misoprostol nationallicence Medical abortion nationallicence Mifepristone nationallicence Dahiya Krishna Department of Obstetrics and Gynecology, Pt. B.D. Sharma PGIMS Rohtak, 74-R, Model Town, 124001, Rohtak, Haryana, India aut Mann Sonika Department of Obstetrics and Gynecology, Pt. B.D. Sharma PGIMS Rohtak, 74-R, Model Town, 124001, Rohtak, Haryana, India aut Nanda Smiti Department of Obstetrics and Gynecology, Pt. B.D. Sharma PGIMS Rohtak, 74-R, Model Town, 124001, Rohtak, Haryana, India aut Archives of Gynecology and Obstetrics Springer-Verlag 284/1(2011-07-01), 59-63 0932-0067 284:1<59 2011 284 404 https://doi.org/10.1007/s00404-010-1590-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1590-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dahiya Krishna Department of Obstetrics and Gynecology, Pt. B.D. Sharma PGIMS Rohtak, 74-R, Model Town, 124001, Rohtak, Haryana, India aut NATIONALLICENCE 700 1- Mann Sonika Department of Obstetrics and Gynecology, Pt. B.D. Sharma PGIMS Rohtak, 74-R, Model Town, 124001, Rohtak, Haryana, India aut NATIONALLICENCE 700 1- Nanda Smiti Department of Obstetrics and Gynecology, Pt. B.D. Sharma PGIMS Rohtak, 74-R, Model Town, 124001, Rohtak, Haryana, India aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/1(2011-07-01), 59-63 0932-0067 284:1<59 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer