caa a22 4500 445309466 CHVBK 20180317142624.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00404-011-2071-y doi (NATIONALLICENCE)springer-10.1007/s00404-011-2071-y Lack of correlation between first trimester maternal serum 25-hydroxyvitamin D levels and ultrasound measured crown-rump length and nuchal translucency [Elektronische Daten] [Ana Fernández-Alonso, Gabriel Fiol-Ruiz, Peter Chedraui, Faustino Pérez-López] Background: Vitamin D regulates the human genome and it is thought to influence the fetal growth and development, but its relation to early ultrasound fetal measures is still unknown. Objective: To assess first trimester 25-hydroxyvitamin D [25(OH)D] maternal serum status and correlate with ultrasound crown-rump length (CRL) and nuchal translucency (NT) measurements. Method: In this cross-sectional study, women with singleton pregnancies undergoing the first trimester standard two-dimensional ultrasound scan for fetal anomalies were included: CRL (n=498) and NT (n=487). Concomitantly, maternal serum 25(OH)D levels were also measured. Results: Median serum 25(OH)D levels for the entire sample (n=498) was 27.4ng/mL (interquartile range 20.9-32.7). Serum 25(OH)D was adequate (≥30ng/mL) in only 36.1% of gravids, whereas levels were found to be insufficient (20-29.99ng/mL) in 41.2% and deficient (<20ng/mL) in 22.7%. No significant correlation was found between the serum 25(OH)D levels and the measured ultrasound parameters. Conclusion: First trimester 25(OH)D levels did not correlate to fetal ultrasound measurements. Springer-Verlag, 2011 25-Hydroxyvitamin D nationallicence Crown-rump length nationallicence Nuchal translucency thickness nationallicence First trimester pregnancy nationallicence Vitamin D nationallicence Fernández-Alonso Ana Departamento de Obstetricia y Ginecología, Hospital Torrecárdenas, Paraje Torrecárdenas s/n, 04009, Almeria, Spain aut Fiol-Ruiz Gabriel Departamento de Obstetricia y Ginecología, Hospital Torrecárdenas, Paraje Torrecárdenas s/n, 04009, Almeria, Spain aut Chedraui Peter Hospital Gineco-Obstétrico Enrique C. Sotomayor, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador aut Pérez-López Faustino Departamento de Obstetricia y Ginecología, Hospital Clínico de Zaragoza, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain aut Archives of Gynecology and Obstetrics Springer-Verlag 284/6(2011-12-01), 1585-1588 0932-0067 284:6<1585 2011 284 404 https://doi.org/10.1007/s00404-011-2071-y text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-2071-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fernández-Alonso Ana Departamento de Obstetricia y Ginecología, Hospital Torrecárdenas, Paraje Torrecárdenas s/n, 04009, Almeria, Spain aut NATIONALLICENCE 700 1- Fiol-Ruiz Gabriel Departamento de Obstetricia y Ginecología, Hospital Torrecárdenas, Paraje Torrecárdenas s/n, 04009, Almeria, Spain aut NATIONALLICENCE 700 1- Chedraui Peter Hospital Gineco-Obstétrico Enrique C. Sotomayor, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador aut NATIONALLICENCE 700 1- Pérez-López Faustino Departamento de Obstetricia y Ginecología, Hospital Clínico de Zaragoza, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/6(2011-12-01), 1585-1588 0932-0067 284:6<1585 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer