caa a22 4500 445309520 CHVBK 20180317142624.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00404-011-1884-z doi (NATIONALLICENCE)springer-10.1007/s00404-011-1884-z Detection and credibility of sentinel node in vulvar cancer: a single institutional study and short review of literature [Elektronische Daten] [Nikolaos Akrivos, Alexandros Rodolakis, George Vlachos, Maria Sotiropoulou, Vasileios Papantoniou, Ioannis Biliatis, Dimitrios Haidopoulos, Nikolaos Thomakos, Maria Simou, Aris Antsaklis] Purpose: To evaluate the detectability and credibility of sentinel lymph node (SLN) in vulvar cancer. Methods: With Tc99m-nanocolloid and methylene blue, we identified SLNs in 34 patients. In 27 cases both tracers were used, while in 7 only blue dye was used. Completion lymphadenectomy was performed in all patients. SLNs and non-SLNs were sent separately for pathologic evaluation. Results: At least one SLN was identified in all patients. Detection rate per groin was not significantly higher in the combined versus blue dye only technique (42/50 vs. 10/14, p=0.43). 99m-Tc was not superior to blue dye in detecting SLN (42/50 vs. 50/64, p=0.65). Midline location of the tumor did not seem to negatively affect the procedure. Four false negatives were observed in three patients with tumors >4cm. Negative predictive value of SLN was 100% for grade I tumors ≤4cm in patients ≤71years. Conclusion: Tc-99m does not seem to be superior to methylene blue in the detection of SLN in vulvar cancer. Patients of younger age with small, well-differentiated tumors appear to be the most suitable candidates for lymphatic mapping. Springer-Verlag, 2011 Sentinel node nationallicence Vulvar cancer nationallicence Blue dye nationallicence Technetium nationallicence Akrivos Nikolaos Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut Rodolakis Alexandros Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut Vlachos George Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut Sotiropoulou Maria Pathology Department, Alexandra Hospital, Athens, Greece aut Papantoniou Vasileios Department of Nuclear Medicine, Alexandra Hospital, Athens, Greece aut Biliatis Ioannis Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut Haidopoulos Dimitrios Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut Thomakos Nikolaos Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut Simou Maria Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut Antsaklis Aris Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut Archives of Gynecology and Obstetrics Springer-Verlag 284/6(2011-12-01), 1551-1556 0932-0067 284:6<1551 2011 284 404 https://doi.org/10.1007/s00404-011-1884-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-1884-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Akrivos Nikolaos Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut NATIONALLICENCE 700 1- Rodolakis Alexandros Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut NATIONALLICENCE 700 1- Vlachos George Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut NATIONALLICENCE 700 1- Sotiropoulou Maria Pathology Department, Alexandra Hospital, Athens, Greece aut NATIONALLICENCE 700 1- Papantoniou Vasileios Department of Nuclear Medicine, Alexandra Hospital, Athens, Greece aut NATIONALLICENCE 700 1- Biliatis Ioannis Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut NATIONALLICENCE 700 1- Haidopoulos Dimitrios Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut NATIONALLICENCE 700 1- Thomakos Nikolaos Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut NATIONALLICENCE 700 1- Simou Maria Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut NATIONALLICENCE 700 1- Antsaklis Aris Department of Obstetrics and Gynecology, Alexandra Hospital, University of Athens, 9, Antheon str, 14235, Athens, Greece aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/6(2011-12-01), 1551-1556 0932-0067 284:6<1551 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer