caa a22 4500 445310073 CHVBK 20180317142626.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s00404-010-1728-2 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1728-2 Iron status parameters in preeclamptic women [Elektronische Daten] [Imran Siddiqui, Anila Jaleel, Hanan Kadri, Waleed Saeed, Waleed Tamimi] Background: Evidence of increased oxidative stress due to endothelial dysfunction in preeclampsia has been well established. Increase in the oxidative stress is catalyzed in the presence of free transitional metals. Therefore, the relationship of iron status with preeclampsia was under investigation. Objective: The objective of the study was to compare red blood cell (RBC) count, hemoglobin (Hb) concentration, hematocrit (Hct), RBC indices, and iron status parameters in preeclamptic and healthy pregnant women. Method: Blood samples were collected from 40 pregnant females diagnosed as preeclampsia and 80 normal pregnant females at the Department of Obstetrics and Gynecology at King Abdulaziz Medical City, Riyadh, Saudi Arabia between February 2009 and January 2010. We recorded RBC count, Hb concentration, Hct, RBC indices, serum iron and ferritin levels in both the groups. Result: Mean serum iron in preeclampsia group was 23.48±9.05, while 12.2±5.21 in normal group (p<0.05). Similarly, mean serum ferritin concentration in preeclamptic and normal pregnant women were 32.56±11.72 and 19.89±8.86, respectively (p<0.05). No significant differences were found among RBC count, Hb concentration, Hct, and RBC indices in both the groups. Conclusion: We recommend that any pregnant female with higher serum iron and ferritin concentrations should be further investigated for preeclampsia. Springer-Verlag, 2010 Preeclampsia nationallicence Serum iron nationallicence Serum ferritin nationallicence Siddiqui Imran College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, MC: 3127, PO Box 22490, 11426, Riyadh, Kingdom of Saudi Arabia aut Jaleel Anila Department of Biochemistry, Ziauddin Medical University, Karachi, Pakistan aut Kadri Hanan Department of OB/GYN, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia aut Saeed Waleed Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia aut Tamimi Waleed College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, MC: 3127, PO Box 22490, 11426, Riyadh, Kingdom of Saudi Arabia aut Archives of Gynecology and Obstetrics Springer-Verlag 284/3(2011-09-01), 587-591 0932-0067 284:3<587 2011 284 404 https://doi.org/10.1007/s00404-010-1728-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1728-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Siddiqui Imran College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, MC: 3127, PO Box 22490, 11426, Riyadh, Kingdom of Saudi Arabia aut NATIONALLICENCE 700 1- Jaleel Anila Department of Biochemistry, Ziauddin Medical University, Karachi, Pakistan aut NATIONALLICENCE 700 1- Kadri Hanan Department of OB/GYN, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia aut NATIONALLICENCE 700 1- Saeed Waleed Department of Pathology and Laboratory Medicine, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia aut NATIONALLICENCE 700 1- Tamimi Waleed College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, MC: 3127, PO Box 22490, 11426, Riyadh, Kingdom of Saudi Arabia aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/3(2011-09-01), 587-591 0932-0067 284:3<587 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer