caa a22 4500 445310219 CHVBK 20180317142627.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s00404-010-1711-y doi (NATIONALLICENCE)springer-10.1007/s00404-010-1711-y The effect of cold stress on polycystic ovary syndrome in rat: before and during modeling [Elektronische Daten] [Farideh Zangeneh, Alireza Abdollahi, Pouyan Tavassoli, Mohammad Naghizadeh] Purpose: The aim of this study was the evaluation effects of a chronic intermittent cold stress regimen before and during PCO modeling in rat. Methods: Forty-eight rats were treated with estradiol valerate for 60days in order to induction of follicular cysts (PCO modeling). Rats were divided into two groups: (1) before (cold stress 3weeks then PCO modeling) and (2) during modeling (cold stress and PCO simultaneous). Results: The biochemical and histological findings show that in simultaneous cold stress and estradiol injection group PCOS modeling has been done successfully and in the other group cold stress prevents induction of PCO in rats. Conclusion: The present study is the first survey that reports 3-week chronic stress before estradiol injection prevents the induction of PCO in rats. Springer-Verlag, 2010 Polycystic ovary syndrome (PCOS) nationallicence Chronic cold stress nationallicence Sympathetic nervous system nationallicence Rat nationallicence Zangeneh Farideh Vali-e-Asr Reproductive Health Research Center, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran aut Abdollahi Alireza Pathology Laboratory, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran aut Tavassoli Pouyan Medicine Faculty, Azad University, Tehran, Iran aut Naghizadeh Mohammad Central Biostatistics, Fasa University of Medical Sciences, Fasa, Iran aut Archives of Gynecology and Obstetrics Springer-Verlag 284/3(2011-09-01), 651-657 0932-0067 284:3<651 2011 284 404 https://doi.org/10.1007/s00404-010-1711-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1711-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zangeneh Farideh Vali-e-Asr Reproductive Health Research Center, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran aut NATIONALLICENCE 700 1- Abdollahi Alireza Pathology Laboratory, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran aut NATIONALLICENCE 700 1- Tavassoli Pouyan Medicine Faculty, Azad University, Tehran, Iran aut NATIONALLICENCE 700 1- Naghizadeh Mohammad Central Biostatistics, Fasa University of Medical Sciences, Fasa, Iran aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/3(2011-09-01), 651-657 0932-0067 284:3<651 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer