caa a22 4500 44531026X CHVBK 20180317142627.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s00404-010-1693-9 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1693-9 Significance of PTPRZ1 and CIN85 expression in cervical carcinoma [Elektronische Daten] [Yaxi Ma, Feng Ye, Xing Xie, Caiyun Zhou, Weiguo Lu] Purpose: To investigate PTPRZ1 and CIN85 expression and their significance in cervical carcinoma. Methods: The expression of PTPRZ1 and CIN85 was detected by immunohistochemistry and the association between PTPRZ1 and CIN85 expression and clinical pathological variables were analyzed. Results: The expression of PTPRZ1 and CIN85 were significantly higher in cervical carcinoma than those in normal cervical epithelium. CIN85 expression was significantly higher in patients with deeper cervical invasion when compared with that with superficial invasion, while PTPRZ1 expression was significantly higher in patients with smaller tumor size (≤2cm) than that with larger size (>2cm). The expression of PTPRZ1 and CIN85 were higher in squamous cell carcinoma than those in adenocarcinoma. Conclusions: There exist increased PTPRZ1 and CIN85 expression in cervical carcinoma and they are probably associated with tumor growth or invasion. PTPRZ1 and CIN85 expression were higher in squamous cell carcinoma than those in adenocarcinoma. Springer-Verlag, 2010 Gynae-oncology nationallicence PTPRZ1 nationallicence CIN85 nationallicence Cervical carcinoma nationallicence Ma Yaxi Department of Gynecology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, 310009, Hangzhou, People's Republic of China aut Ye Feng Department of Gynecologic Oncology, The Women's Hospital, School of Medicine, Zhejiang University, 310006, Hangzhou, People's Republic of China aut Xie Xing Department of Gynecologic Oncology, The Women's Hospital, School of Medicine, Zhejiang University, 310006, Hangzhou, People's Republic of China aut Zhou Caiyun Department of Gynecologic Oncology, The Women's Hospital, School of Medicine, Zhejiang University, 310006, Hangzhou, People's Republic of China aut Lu Weiguo Department of Gynecologic Oncology, The Women's Hospital, School of Medicine, Zhejiang University, 310006, Hangzhou, People's Republic of China aut Archives of Gynecology and Obstetrics Springer-Verlag 284/3(2011-09-01), 699-704 0932-0067 284:3<699 2011 284 404 https://doi.org/10.1007/s00404-010-1693-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1693-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ma Yaxi Department of Gynecology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, 310009, Hangzhou, People's Republic of China aut NATIONALLICENCE 700 1- Ye Feng Department of Gynecologic Oncology, The Women's Hospital, School of Medicine, Zhejiang University, 310006, Hangzhou, People's Republic of China aut NATIONALLICENCE 700 1- Xie Xing Department of Gynecologic Oncology, The Women's Hospital, School of Medicine, Zhejiang University, 310006, Hangzhou, People's Republic of China aut NATIONALLICENCE 700 1- Zhou Caiyun Department of Gynecologic Oncology, The Women's Hospital, School of Medicine, Zhejiang University, 310006, Hangzhou, People's Republic of China aut NATIONALLICENCE 700 1- Lu Weiguo Department of Gynecologic Oncology, The Women's Hospital, School of Medicine, Zhejiang University, 310006, Hangzhou, People's Republic of China aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/3(2011-09-01), 699-704 0932-0067 284:3<699 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer