caa a22 4500 445310391 CHVBK 20180317142627.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00404-011-1963-1 doi (NATIONALLICENCE)springer-10.1007/s00404-011-1963-1 Matevosyan Naira Alumna of the Open Medical Insitute, Salzburg, Austria aut Schizophrenia and Stein-Leventhal syndrome: comorbidity features [Elektronische Daten] [Naira Matevosyan] Objective: To explore shared pathogenesis between schizophrenia and polycistic ovary syndrome (PCOS). Methods: Ninety-six studies of schizophrenia and PCOS from a mean sample of 139 women are recruited from PubMed and FASTSTATS for geometrical regression analysis. Parametric and observational properties of both diseases (gene polymorphism, monoamines, gonadal steroids, gonadotropins, thyroid hormones, insulin sensitivity index, hirsute index, oligomenorrhea, anhedonia, asociality, apathy, emotional withdrawal, alogia, poor rapport, stereotypical thinking, hyperkinetic reactions, treatment with valproate) are stochastically distributed in the elliptical area. Results: Results of both analyses suggest that insulin resistance and elevated testosterone are predictive to comorbidity. These associations are stronger with calculation from elliptical model (r 2=0.92) than a traditional regression analysis (r 2=0.65). Conclusions: Insulin resistance and elevated testosterone in women contribute in shared pathogenesis of schizophrenia and PCOS. 3D regression analysis shows greater strength of association with the "criterion” value. Springer-Verlag, 2011 3D regression nationallicence Comorbidity nationallicence Schizophrenia nationallicence Stein-Leventhal syndrome nationallicence Insulin resistance nationallicence Testosterone nationallicence Archives of Gynecology and Obstetrics Springer-Verlag 284/4(2011-10-01), 1035-1041 0932-0067 284:4<1035 2011 284 404 https://doi.org/10.1007/s00404-011-1963-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-1963-1 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Matevosyan Naira Alumna of the Open Medical Insitute, Salzburg, Austria aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/4(2011-10-01), 1035-1041 0932-0067 284:4<1035 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer