caa a22 4500 44531057X CHVBK 20180317142628.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00404-010-1740-6 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1740-6 Maternal early pregnancy body mass index and risk of preterm birth [Elektronische Daten] [Ting Wang, Jun Zhang, Xinrong Lu, Wei Xi, Zhu Li] Objective: To determine the association between maternal body mass index (BMI) in early pregnancy and the risk of preterm birth (PTB) in Chinese women. Methods: Data were obtained from a population-based perinatal care program in China during 1993-2005. Women whose height and weight information was recorded at the first prenatal visit in the first trimester of pregnancy and delivered a singleton live infant were selected. Women with multiple gestations, stillbirths, delivery before 28weeks or after 44weeks of gestation, and infants affected by major external birth defects were excluded. BMI was categorized as underweight (less than 18.5kg/m2), normal weight (18.5-23.9kg/m2), overweight (24-27.9kg/m2), and obese (≥28kg/m2) based on BMI classification criteria for Chinese. Logistic regression analysis was conducted to adjust for potential confounders, such as maternal age, education, occupation, city or county, gender of infant, and year of delivery. Results: A total of 353,477 women were selected. The incidence of preterm birth in women who were underweight, normal weight, overweight, obese was 3.69% (3.61-3.76%), 3.59% (3.55-3.62%), 3.83% (3.71-3.96%), 4.90% (4.37-5.43%), respectively. The incidence of elective preterm birth, overweight, and obesity increased remarkably during 2000-2005 compared with that during 1993-1996. After having adjusted for potential confounders including maternal age, maternal occupation, education, city or county, gender of the infant and year of birth, the risk of PTB increased significantly with BMI (P<0.05). Among nulliparae, the risk of elective preterm birth increased with increasing BMI. Nulliparae who were underweight were less likely to deliver elective preterm births (OR=0.89, 95% CI 0.80-0.98). Nulliparae who were overweight and obese in early pregnancy were at a greater risk of elective PTB than normal weight nulliparae (for the overweight OR=1.36, 95% CI 1.18-1.56, for the obese OR=2.94, 95% CI 2.04-4.25). Conclusion: In this study, indigenous Chinese cohort women who are overweight, obese, and nulliparous are at an increased risk of elective preterm birth. Springer-Verlag, 2010 Preterm birth nationallicence Body mass index nationallicence Early pregnancy nationallicence Parity nationallicence Obesity nationallicence BMI : Body mass index nationallicence CI : Confidence interval nationallicence IRB : Institutional review board nationallicence MCH : Maternity and child health nationallicence NCMIH : National Center for Maternal and Infant Health nationallicence OR : Odds ratio nationallicence PTB : Preterm birth nationallicence PHCSS : Perinatal Health Care Surveillance System nationallicence SD : Standard deviation nationallicence Wang Ting School of Public Health Peking University Health Science Center, 38 Xueyuan Rd Haidian District, 100191, Beijing, People's Republic of China aut Zhang Jun Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 200092, Shanghai, China aut Lu Xinrong School of Public Health Peking University Health Science Center, 38 Xueyuan Rd Haidian District, 100191, Beijing, People's Republic of China aut Xi Wei School of Public Health Peking University Health Science Center, 38 Xueyuan Rd Haidian District, 100191, Beijing, People's Republic of China aut Li Zhu School of Public Health Peking University Health Science Center, 38 Xueyuan Rd Haidian District, 100191, Beijing, People's Republic of China aut Archives of Gynecology and Obstetrics Springer-Verlag 284/4(2011-10-01), 813-819 0932-0067 284:4<813 2011 284 404 https://doi.org/10.1007/s00404-010-1740-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1740-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Ting School of Public Health Peking University Health Science Center, 38 Xueyuan Rd Haidian District, 100191, Beijing, People's Republic of China aut NATIONALLICENCE 700 1- Zhang Jun Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 200092, Shanghai, China aut NATIONALLICENCE 700 1- Lu Xinrong School of Public Health Peking University Health Science Center, 38 Xueyuan Rd Haidian District, 100191, Beijing, People's Republic of China aut NATIONALLICENCE 700 1- Xi Wei School of Public Health Peking University Health Science Center, 38 Xueyuan Rd Haidian District, 100191, Beijing, People's Republic of China aut NATIONALLICENCE 700 1- Li Zhu School of Public Health Peking University Health Science Center, 38 Xueyuan Rd Haidian District, 100191, Beijing, People's Republic of China aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/4(2011-10-01), 813-819 0932-0067 284:4<813 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer