caa a22 4500 445310715 CHVBK 20180317142628.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s00404-010-1783-8 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1783-8 Effect of anesthesiological strategies on neonatal bilirubin levels during cesarean section: a prospective and randomized trial [Elektronische Daten] [Yavuz Demiraran, Mustafa Albayrak, Ilknur Seker, Gursel Kaynak, Abdulkadir Iskender, Gulbin Sezen, Ismail Ozdemir] Purpose: Neonatal jaundice, a frequent problem in neonatology, can be influenced by many factors. Here, we sought to clarify the role of anesthesia and to compare the effects of various anesthesiological strategies on neonatal bilirubin levels during cesarean section. Methods: We prospectively enrolled 167 ASA I-II status uncomplicated pregnant women who delivered by cesarean section as the study group. The patients were randomized based on anesthesiological strategy: inhalation (IA), spinal (SA), total intravenous (TIVA), and epidural anesthesia (EA) groups. Neonatal total (TB) and direct bilirubin (DB) levels at the 24th hour and 5th day of life and the need for phototherapy were compared between the groups. Results: Direct bilirubin levels at 24th hour of SA group and EA group were higher compared to IA group (p=0.008). When DB levels at fifth day were compared, levels in group TIVA were significantly higher than group SA (p=0.019). TB levels at fifth day in group TIVA were higher than SA and EA groups (p=0.05). The percentage of newborns needing phototherapy did not differ significantly among groups, but was highest in the TIVA group (25%), followed by the IA (15%), EA (10%) and SA (7%) groups (p=0.08). Conclusions: EA and SA at cesarean section seem to be better among the four anesthesia techniques considering neonatal hyperbilirubinemia. Our findings are consistent with the idea that anesthesia may be a risk factor for hyperbilirubinemia. Although anesthesia may not significantly increase the need for interventions such as phototherapy, it may increase the burden of time, labor and cost. Springer-Verlag, 2010 Anesthesia technique nationallicence Neonatal jaundice nationallicence Cesarean section nationallicence Demiraran Yavuz Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut Albayrak Mustafa Department of Obstetrics and Gynecology, Duzce University School of Medicine, 81620, Duzce, Konuralp, Turkey aut Seker Ilknur Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut Kaynak Gursel Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut Iskender Abdulkadir Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut Sezen Gulbin Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut Ozdemir Ismail Department of Obstetrics and Gynecology, Duzce University School of Medicine, 81620, Duzce, Konuralp, Turkey aut Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1059-1065 0932-0067 284:5<1059 2011 284 404 https://doi.org/10.1007/s00404-010-1783-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1783-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Demiraran Yavuz Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut NATIONALLICENCE 700 1- Albayrak Mustafa Department of Obstetrics and Gynecology, Duzce University School of Medicine, 81620, Duzce, Konuralp, Turkey aut NATIONALLICENCE 700 1- Seker Ilknur Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut NATIONALLICENCE 700 1- Kaynak Gursel Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut NATIONALLICENCE 700 1- Iskender Abdulkadir Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut NATIONALLICENCE 700 1- Sezen Gulbin Departments of Anesthesiology and Reanimation, Duzce University School of Medicine, Duzce, Turkey aut NATIONALLICENCE 700 1- Ozdemir Ismail Department of Obstetrics and Gynecology, Duzce University School of Medicine, 81620, Duzce, Konuralp, Turkey aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1059-1065 0932-0067 284:5<1059 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer