caa a22 4500 445310731 CHVBK 20180317142628.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s00404-010-1785-6 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1785-6 Umbilical vein oxytocin in the management of retained placenta: an alternative to manual removal of placenta? [Elektronische Daten] [Pei Lim, Surinder Singh, Alice Lee, Muhammad Muhammad Yassin] Purpose: Retained placenta is potentially life threatening due to possible complications associated with manual removal. Our aim was to determine whether umbilical vein injection of oxytocin in saline reduces the need for manual removal of placenta. Methods: This was a randomised controlled trial conducted at a tertiary hospital from December 2002 to March 2004. A total of 61 women delivering singletons, who had no sign of placental separation 20min after vaginal delivery, were randomised to receive either intra-umbilical oxytocin 100IU diluted in 30ml of saline or controlled cord traction only. Manual removal was done if the placenta was not expelled in another 30min in both arms. Results: There was a significant reduction in the rate of subsequent manual removal of placenta (30 vs. 67.7%, p<0.05), incidence of uterine atony (3.3 vs. 25.8%, p<0.05) and the need for uterotonic agents (33.3 vs. 64.5%, p<0.05) in the oxytocin group when compared with the control group. No significant differences were found in the need for blood transfusion, uterine curettage, incidence of postpartum haemorrhage and haemoglobin level reduction. Conclusion: Intra-umbilical vein oxytocin injection is clinically effective for the management of a retained placenta. Springer-Verlag, 2010 Intra-umbilical nationallicence Oxytocin nationallicence Retained nationallicence Placenta nationallicence Umbilical vein nationallicence Lim Pei Department of O&G, Universiti Kebangsaan Malaysia Medical Center, Jalan Yaakob Latif, 56000, Cheras, Kuala Lumpur, Malaysia aut Singh Surinder Tropicana Medical Center, 11, Jalan Teknologi, Taman Sains Selangor, Petaling Jaya, Selangor, Malaysia aut Lee Alice Damansara Fertility Centre, Level 1, Unit 18, Citiplaza, No. 21, Jalan Tebrau, 80300, Johor Bahru, Johor, Malaysia aut Muhammad Yassin Muhammad Department of O&G, Universiti Kebangsaan Malaysia Medical Center, Jalan Yaakob Latif, 56000, Cheras, Kuala Lumpur, Malaysia aut Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1073-1079 0932-0067 284:5<1073 2011 284 404 https://doi.org/10.1007/s00404-010-1785-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1785-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lim Pei Department of O&G, Universiti Kebangsaan Malaysia Medical Center, Jalan Yaakob Latif, 56000, Cheras, Kuala Lumpur, Malaysia aut NATIONALLICENCE 700 1- Singh Surinder Tropicana Medical Center, 11, Jalan Teknologi, Taman Sains Selangor, Petaling Jaya, Selangor, Malaysia aut NATIONALLICENCE 700 1- Lee Alice Damansara Fertility Centre, Level 1, Unit 18, Citiplaza, No. 21, Jalan Tebrau, 80300, Johor Bahru, Johor, Malaysia aut NATIONALLICENCE 700 1- Muhammad Yassin Muhammad Department of O&G, Universiti Kebangsaan Malaysia Medical Center, Jalan Yaakob Latif, 56000, Cheras, Kuala Lumpur, Malaysia aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1073-1079 0932-0067 284:5<1073 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer