caa a22 4500 445310855 CHVBK 20180317142629.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s00404-011-1979-6 doi (NATIONALLICENCE)springer-10.1007/s00404-011-1979-6 Different serum anti-Müllerian hormone concentrations are associated with oocyte quality, embryo development parameters and IVF-ICSI outcomes [Elektronische Daten] [Tulay Irez, Pelin Ocal, Onur Guralp, Meral Cetin, Begum Aydogan, Sezai Sahmay] Objective: To evaluate the association between different basal serum levels of anti-Müllerian hormone (AMH) and oocyte-embryo quality and IVF outcomes. Materials and methods: Two hundred and nine infertile women who underwent in vitro fertilization treatment with intracytoplasmic sperm injection (ICSI) between January 2009 and February 2011 were included in the study. Mean age, BMI, FSH, E2, inhibin B, duration of infertility, total gonadotropin dose, antral follicle count, morphology of all oocytes, percentage of MII, early cleavage rate, the number of good quality embryos in transfer and ongoing pregnancy (>12weeks) rates were evaluated. Results: Six groups were formed according to the percentiles as <10% (≤0.89ng/ml; n=21), 10-25% (0.89-1.40ng/ml; n=31), 25-50% (1.40-2.89ng/ml; n=53), 50-75% (2.89-4.83ng/ml; n=28), 75-90% (4.83-8.06ng/ml; n=55), >90% (>8.06ng/ml; n=21). Central granulation, cytoplasmic granulation, oocyte postmaturity, percentage of embryos, early cleavage and percentage of transferred good quality embryos were significantly different in five groups (ANOVA test). Ongoing pregnancy rate (PR) was the lowest in <10% (9.5%), and the highest in 50-75% group (39.3%). (P= 0.040) Conclusion: Different AMH levels may predict the quality of oocytes, presence of postmaturity and nucleoli Z score, early cleavage and ICSI outcomes. Springer-Verlag, 2011 AMH nationallicence Oocyte quality nationallicence Embryo quality nationallicence ICSI outcomes nationallicence Irez Tulay Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut Ocal Pelin Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut Guralp Onur Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut Cetin Meral Department of Obstetrics and Gynecology, School of Medicine, Cumhuriyet University, Sivas, Turkey aut Aydogan Begum Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut Sahmay Sezai Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1295-1301 0932-0067 284:5<1295 2011 284 404 https://doi.org/10.1007/s00404-011-1979-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-1979-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Irez Tulay Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut NATIONALLICENCE 700 1- Ocal Pelin Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut NATIONALLICENCE 700 1- Guralp Onur Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut NATIONALLICENCE 700 1- Cetin Meral Department of Obstetrics and Gynecology, School of Medicine, Cumhuriyet University, Sivas, Turkey aut NATIONALLICENCE 700 1- Aydogan Begum Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut NATIONALLICENCE 700 1- Sahmay Sezai Department of Obstetrics and Gynecology, Cerrahpasa School of Medicine, Istanbul University, IVF Unit, Istanbul, Turkey aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1295-1301 0932-0067 284:5<1295 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer