caa a22 4500 445310960 CHVBK 20180317142629.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s00404-010-1810-9 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1810-9 Gestational diabetes: a strong independent risk factor for severe neonatal respiratory failure after 34weeks [Elektronische Daten] [Pauline Vignoles, Catherine Gire, Julien Mancini, Florence Bretelle, Léon Boubli, Eustase Janky, Xavier Carcopino] Purpose: To evaluate if gestational diabetes (GD) exposes neonates delivered after 34weeks to an increased risk of severe neonatal respiratory failure (NRF). Methods: Data from 3,237 women who delivered after 34weeks with systematic screening for GD were analyzed. Diagnosis of severe NRF required the association of clinical and radiological criteria with a minimum of 24h of ventilation and admission to neonatal intensive care unit. Results: A total of 166 (5.1%) cases of GD were identified. Severe NRF was diagnosed in 7 (4.21%) cases among women with GD as compared to 13 (0.42%) in others (p<0.001). The rate of severe NRF was also significantly higher in cases of premature delivery (p<0.001), fetal growth retardation (p<0.001), and cesarean section (p=0.005). After adjustment for these variables, GD was identified as an independent risk factor for NRF (AOR 11.55, 95% CI 3.9-33.9, p<0.001). Two other risk factors were also identified: late preterm delivery (AOR 6.13, 95% CI 1.8-21.2, p=0.004); and hypotrophy (AOR 9.16, 95% CI 2.7-30.5, p<0.001). Conclusions: GD is an independent risk factor for severe NRF after 34weeks. Neonates from such pregnancies should be monitored carefully. Springer-Verlag, 2010 Diabetes mellitus nationallicence Gestational diabetes nationallicence Neonatal respiratory failure nationallicence Ventilation nationallicence Late preterm delivery nationallicence Vignoles Pauline Service de Gynécologie Obstétrique, Hôpital de Pointe-à Pitre Abymes, 97159, Pointe à Pitre Cedex, Guadeloupe, France aut Gire Catherine Service de Pédiatrie, Hôpital Nord, Chemin des Bourrely, 13915 Cedex 20, Marseille, France aut Mancini Julien Service Santé Publique, Hôpital de la Timone, 264, Rue Saint-Pierre, 13385, Marseille Cedex 5, France aut Bretelle Florence Service de Gynécologie Obstétrique, Hôpital Nord, Chemin des Bourrely, 13915 Cedex 20, Marseille, France aut Boubli Léon Service de Gynécologie Obstétrique, Hôpital Nord, Chemin des Bourrely, 13915 Cedex 20, Marseille, France aut Janky Eustase Service de Gynécologie Obstétrique, Hôpital de Pointe-à Pitre Abymes, 97159, Pointe à Pitre Cedex, Guadeloupe, France aut Carcopino Xavier Service de Gynécologie Obstétrique, Hôpital Nord, Chemin des Bourrely, 13915 Cedex 20, Marseille, France aut Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1099-1104 0932-0067 284:5<1099 2011 284 404 https://doi.org/10.1007/s00404-010-1810-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1810-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vignoles Pauline Service de Gynécologie Obstétrique, Hôpital de Pointe-à Pitre Abymes, 97159, Pointe à Pitre Cedex, Guadeloupe, France aut NATIONALLICENCE 700 1- Gire Catherine Service de Pédiatrie, Hôpital Nord, Chemin des Bourrely, 13915 Cedex 20, Marseille, France aut NATIONALLICENCE 700 1- Mancini Julien Service Santé Publique, Hôpital de la Timone, 264, Rue Saint-Pierre, 13385, Marseille Cedex 5, France aut NATIONALLICENCE 700 1- Bretelle Florence Service de Gynécologie Obstétrique, Hôpital Nord, Chemin des Bourrely, 13915 Cedex 20, Marseille, France aut NATIONALLICENCE 700 1- Boubli Léon Service de Gynécologie Obstétrique, Hôpital Nord, Chemin des Bourrely, 13915 Cedex 20, Marseille, France aut NATIONALLICENCE 700 1- Janky Eustase Service de Gynécologie Obstétrique, Hôpital de Pointe-à Pitre Abymes, 97159, Pointe à Pitre Cedex, Guadeloupe, France aut NATIONALLICENCE 700 1- Carcopino Xavier Service de Gynécologie Obstétrique, Hôpital Nord, Chemin des Bourrely, 13915 Cedex 20, Marseille, France aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1099-1104 0932-0067 284:5<1099 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer