caa a22 4500 445310987 CHVBK 20180317142629.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s00404-010-1793-6 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1793-6 Comparison of Pap smear, visual inspection with acetic acid, and digital cervicography as cervical screening strategies [Elektronische Daten] [Nahid Khodakarami, Farah Farzaneh, Fatemeh Aslani, Kamyab Alizadeh] Purpose: To compare the sensitivity, specificity, positive and negative predictive values (PPV and NPV), and accuracy of Pap smear, visual inspection with acetic acid (VIA) and digital cervicography (DC). Methods: This is a cross-sectional study on 100 women in the age group of 20-60years, sequentially using the Pap test, the VIA, and the DC for screening. All women underwent colposcopic biopsy as the gold standard in comparing the methods. Results: Of the total of 100 women with the mean age 36.0years, 17 cases were recognized positive for abnormal cervical cell by gold standard. The sensitivity, specificity, PPV, NPV, and accuracy of the Pap test, the VIA, and the DC were 23.5, 100, 100, 86.5, and 87%; 62.5, 98.8, 90.9, 93.2, and 92.9%; and 46.7, 97.6, 77.8, 91, and 89.8%, respectively, for cervical neoplasia. Conclusions: The Pap test had low sensitivity but high specificity, whereas VIA had a high sensitivity in addition to being easy and low-cost. Adjuvant methods of screening such as VIA can be a valuable alternative to the Pap test for cervical cancer screening in low-resource settings. Springer-Verlag, 2010 Cervical cancer screening nationallicence Pap smear nationallicence VIA nationallicence Digital cervicography nationallicence Khodakarami Nahid Department of Obstetrics and Gynecology, Gynecology Cancer Research Center, Imam Hossein Hospital, Shaheed Beheshti Medical University, 1617763141, Tehran, Iran aut Farzaneh Farah Department of Obstetrics and Gynecology, Gynecology Cancer Research Center, Imam Hossein Hospital, Shaheed Beheshti Medical University, 1617763141, Tehran, Iran aut Aslani Fatemeh Midwifery School, Shaheed Beheshti Medical University, Tehran, Iran aut Alizadeh Kamyab Department of Obstetrics and Gynecology, Gynecology Cancer Research Center, Imam Hossein Hospital, Shaheed Beheshti Medical University, 1617763141, Tehran, Iran aut Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1247-1252 0932-0067 284:5<1247 2011 284 404 https://doi.org/10.1007/s00404-010-1793-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1793-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Khodakarami Nahid Department of Obstetrics and Gynecology, Gynecology Cancer Research Center, Imam Hossein Hospital, Shaheed Beheshti Medical University, 1617763141, Tehran, Iran aut NATIONALLICENCE 700 1- Farzaneh Farah Department of Obstetrics and Gynecology, Gynecology Cancer Research Center, Imam Hossein Hospital, Shaheed Beheshti Medical University, 1617763141, Tehran, Iran aut NATIONALLICENCE 700 1- Aslani Fatemeh Midwifery School, Shaheed Beheshti Medical University, Tehran, Iran aut NATIONALLICENCE 700 1- Alizadeh Kamyab Department of Obstetrics and Gynecology, Gynecology Cancer Research Center, Imam Hossein Hospital, Shaheed Beheshti Medical University, 1617763141, Tehran, Iran aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/5(2011-11-01), 1247-1252 0932-0067 284:5<1247 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer