caa a22 4500 445311134 CHVBK 20180317142630.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00404-010-1659-y doi (NATIONALLICENCE)springer-10.1007/s00404-010-1659-y Malnutrition as a predictor of poor postoperative outcomes in gynecologic cancer patients [Elektronische Daten] [Anupama Kathiresan, Kathleen Brookfield, Samer Schuman, Joseph Lucci III] Purpose: Poor nutritional status has been associated with increased postoperative morbidity and mortality in surgical patients. The purpose of this study is to evaluate if decreased nutritional parameters correlate with increased postoperative complications regardless of other risk factors in the gynecologic cancer patient. Methods: A retrospective chart review was performed among women who underwent surgical management for gynecologic malignancies from October 2006 to June 2008. Variables included age, race, medical comorbidities, cancer type/stage, preoperative albumin, absolute lymphocyte count (ALC), and body mass index (BMI), estimated blood loss (EBL), intraoperative blood transfusion (BT), intraoperative or postoperative complications, intensive care unit (ICU) admissions, hospital readmissions, reoperations, and cancer recurrence. Results: Three hundred gynecologic oncology patients with preoperative nutritional parameters were included in the study. Decreased albumin was significantly associated with more postoperative complications (p<0.001), hospital readmissions (p=0.01), reoperations (p=0.03), ICU admissions (p<0.001), and cancer recurrence (p<0.001). Decreased ALC and BMI preoperatively was also significantly associated with higher incidence of cancer recurrence (p=0.01, p=0.01). Surgical cases involving increased EBL (p=0.01, p<0.001) and more BT (p<0.001, p<0.001) had significantly more postoperative complications and more ICU admissions. Multivariable logistic regression found preoperative albumin to be an independent predictor of increased postoperative complications. Conclusions: Decreased albumin is significantly associated with more postoperative complications, hospital readmissions, reoperations, ICU admissions, and cancer recurrence. This nutritional parameter is an important predictor of postoperative morbidity and mortality. Thus, it is important to assess nutritional status preoperatively and offer nutritional support or alternate treatment options if necessary. Springer-Verlag, 2010 Malnutrition nationallicence Albumin nationallicence Postoperative complications nationallicence Gynecology oncology nationallicence Kathiresan Anupama Department of Obstetrics and Gynecology, Miller School of Medicine, Jackson Memorial Hospital, University of Miami, 1611 NW 12th Avenue, Holtz Building Suite 4070, 33136, Miami, FL, USA aut Brookfield Kathleen Department of Obstetrics and Gynecology, Miller School of Medicine, Jackson Memorial Hospital, University of Miami, 1611 NW 12th Avenue, Holtz Building Suite 4070, 33136, Miami, FL, USA aut Schuman Samer Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Miller School of Medicine, Jackson Memorial Hospital, 1475 NW 12th Avenue, SCCC 3500, 33136, Miami, FL, USA aut Lucci III Joseph Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Miller School of Medicine, Jackson Memorial Hospital, 1475 NW 12th Avenue, SCCC 3500, 33136, Miami, FL, USA aut Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 445-451 0932-0067 284:2<445 2011 284 404 https://doi.org/10.1007/s00404-010-1659-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1659-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kathiresan Anupama Department of Obstetrics and Gynecology, Miller School of Medicine, Jackson Memorial Hospital, University of Miami, 1611 NW 12th Avenue, Holtz Building Suite 4070, 33136, Miami, FL, USA aut NATIONALLICENCE 700 1- Brookfield Kathleen Department of Obstetrics and Gynecology, Miller School of Medicine, Jackson Memorial Hospital, University of Miami, 1611 NW 12th Avenue, Holtz Building Suite 4070, 33136, Miami, FL, USA aut NATIONALLICENCE 700 1- Schuman Samer Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Miller School of Medicine, Jackson Memorial Hospital, 1475 NW 12th Avenue, SCCC 3500, 33136, Miami, FL, USA aut NATIONALLICENCE 700 1- Lucci III Joseph Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Miller School of Medicine, Jackson Memorial Hospital, 1475 NW 12th Avenue, SCCC 3500, 33136, Miami, FL, USA aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 445-451 0932-0067 284:2<445 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer