caa a22 4500 445311223 CHVBK 20180317142630.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00404-011-1900-3 doi (NATIONALLICENCE)springer-10.1007/s00404-011-1900-3 Prenatal diagnosis of OEIS (omphalocele, bladder exstrophy, imperforate anus, clubfeet) variant associated with increased nuchal translucency and OEIS complex with ambiguous genitalia associated with corrected transposition of the great arteries: case series and review of the literature [Elektronische Daten] [G. Tonni, G. Grisolia, M. Bonasoni, M. Panteghini, I. Vito, C. De Felice] Introduction: The OEIS complex refers to a combination of defects consisting in omphalocele, bladder exstrophy, imperforate anus and spinal defects and represents a rare nosologic entity (from 1:200,000 to 1:400,000 pregnancies). The defect probably occurs in early blastogenesis or in mesodermal migration during the primitive streak period. Materials and methods: Two cases of OEIS complex diagnosed prenatally by ultrasound are reported. The medical record regarding differential diagnosis, associated anomalies, treatment and prognosis has also been sought and reported. Conclusion: Differential diagnosis with exstrophy-epispadias complex and/or cloacalexstrophy complex may be difficult antenatally by means of ultrasound. However, color Doppler has been proved to aid the diagnosis of bladder exstrophy by depicting the urine flow in direct communication with the abdominal cavity and has been useful in showing the course of the perivesical umbilical arteries. Prenatal 3D ultrasound with tomographic ultrasound imaging (TUI) and antenatal MR imaging might be useful adjuncts to conventional 2D scan in aiding the prenatal diagnosis of such malformation. Springer-Verlag, 2011 OEIS complex nationallicence Ambiguous genitalia nationallicence Transposition of the great arteries nationallicence Increased nuchal translucency nationallicence Prenatal diagnosis nationallicence 3D ultrasound nationallicence Tonni G. Prenatal Diagnostic Service, AUSL Reggio Emilia, Via Amendola, 1, 42100, Reggio Emilia, Italy aut Grisolia G. Prenatal Diagnostic Service, Azienda Ospedaliera "Carlo Poma”, Mantua, Mantua, Italy aut Bonasoni M. Pathologic Anatomy, Arcispedale "Santa Maria Nuova”, Reggio Emilia, Italy aut Panteghini M. Prenatal Diagnostic Service, AUSL Reggio Emilia, Via Amendola, 1, 42100, Reggio Emilia, Italy aut Vito I. Prenatal Diagnostic Service, AUSL Reggio Emilia, Via Amendola, 1, 42100, Reggio Emilia, Italy aut De Felice C. Neonatal Intensive Care Unit, Hospital "Santa Maria alle Scotte”, University of Siena, Siena, Italy aut Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 261-269 0932-0067 284:2<261 2011 284 404 https://doi.org/10.1007/s00404-011-1900-3 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-1900-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tonni G. Prenatal Diagnostic Service, AUSL Reggio Emilia, Via Amendola, 1, 42100, Reggio Emilia, Italy aut NATIONALLICENCE 700 1- Grisolia G. Prenatal Diagnostic Service, Azienda Ospedaliera "Carlo Poma”, Mantua, Mantua, Italy aut NATIONALLICENCE 700 1- Bonasoni M. Pathologic Anatomy, Arcispedale "Santa Maria Nuova”, Reggio Emilia, Italy aut NATIONALLICENCE 700 1- Panteghini M. Prenatal Diagnostic Service, AUSL Reggio Emilia, Via Amendola, 1, 42100, Reggio Emilia, Italy aut NATIONALLICENCE 700 1- Vito I. Prenatal Diagnostic Service, AUSL Reggio Emilia, Via Amendola, 1, 42100, Reggio Emilia, Italy aut NATIONALLICENCE 700 1- De Felice C. Neonatal Intensive Care Unit, Hospital "Santa Maria alle Scotte”, University of Siena, Siena, Italy aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 261-269 0932-0067 284:2<261 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer