caa a22 4500 445311274 CHVBK 20180317142630.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00404-010-1660-5 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1660-5 Predictive value of middle cerebral artery to uterine artery pulsatility index ratio in preeclampsia [Elektronische Daten] [Ahmet Eser, Ebru Zulfıkaroglu, Suleyman Eserdag, Sevtap Kılıc, Nurı Danısman] Objective: To determine the predictive value of middle cerebral artery (MCA) to uterine artery pulsatility index (PI) ratio in preeclamptic patients. Methods: This prospective cross-sectional study was performed on 64 preeclamptic and 131 normal pregnancies at or beyond 26weeks of gestation between June 2007-August 2008 in the high-risk pregnancy unit of Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, Ankara. Doppler blood flow velocimetry of the uterine and umbilical arteries and fetal MCA was measured. The ratios between the PI of MCA and the mean PI value of both uterine arteries were calculated and values below the fifth percentile were considered as brain-sparing. The ratios between the PI of MCA and PI of the umbilical artery were calculated and values lower than 1.08 were considered as brain-sparing and the results were related to perinatal outcome. Statistical analysis were performed using the SPSS Software (SPSS, Chicago, IL, USA) version 9.0 for Windows. Odds ratio with 95% confidence interval (95%) was also used for statistical analysis. Results: In 11 (42.3%) of the preeclamptic pregnancies that had abnormal MCA/uterine artery PI, 4 of them had severe preeclampsia and 7 had mild preeclampsia. In the low MCA/uterine artery PI ratio group, a statistically significantly higher rate of Cesarean section (66 vs. 88.46%), NICU admission (26.3 vs. 57.6%), preterm birth (52.6 vs. 92.3%) was found. Abnormal MCA/uterine artery PI ratio and abnormal MCA/umbilical artery PI ratio in the prediction of adverse outcome of pregnancy was compared. In the prediction of preterm birth, which was better for the MCA/uterine artery, there was a significant difference between the ratios (P=0.005). Conclusion: Our results suggest that MCA/uterine artery PI ratio is a good predictor of neonatal outcome in preeclamptic patients in the third trimester and could be used to identify fetuses at risk of morbidity and mortality. Springer-Verlag, 2010 Doppler ultrasound nationallicence MCA/uterine artery PI ratio nationallicence Brain-sparing nationallicence Preeclampsia nationallicence Perinatal outcome nationallicence Eser Ahmet Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut Zulfıkaroglu Ebru Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut Eserdag Suleyman Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut Kılıc Sevtap Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut Danısman Nurı Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 307-311 0932-0067 284:2<307 2011 284 404 https://doi.org/10.1007/s00404-010-1660-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1660-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Eser Ahmet Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Zulfıkaroglu Ebru Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Eserdag Suleyman Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Kılıc Sevtap Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut NATIONALLICENCE 700 1- Danısman Nurı Department of Obstetrics and Gynecology, Ankara Dr. Zekai Tahir Burak Women Health Teaching and Research Hospital, 06100, Ankara, Turkey aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 307-311 0932-0067 284:2<307 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer