caa a22 4500 445311398 CHVBK 20180317142631.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00404-010-1673-0 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1673-0 Can visual inspection with acetic acid under magnification substitute colposcopy in detecting cervical intraepithelial neoplasia in low-resource settings? [Elektronische Daten] [Pakhee Aggarwal, Swaraj Batra, Gauri Gandhi, Vijay Zutshi] Purpose: To compare the sensitivity, specificity, positive and negative predictive values and accuracy of visual inspection with acetic acid under magnification (VIAM) and colposcopy for detecting cervical intraepithelial neoplasia (CIN) to determine if VIAM can substitute colposcopy in identifying the biopsy site in screen-positive cases. Methods: A prospective cross-sectional study was carried out on 408 symptomatic multiparous women in the reproductive age group (15-49years) at a tertiary care teaching hospital. VIAM and colposcopy were used to screen for cervical precancerous lesions. Screen-positive women underwent guided biopsy and endocervical curettage. The site of biopsy was recorded as VIAM guided or colposcopy guided. Histopathology was taken as the gold standard. Results: The mean age was 32.3±6.8years (range 15-49), whilst the mean parity was 2.9±1.2 (range 1-9). A total of 113 women screened positive. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of VIAM and colposcopy were 95, 78, 19, 99 and 79%, and 86, 79, 18, 99 and 79%, respectively for high-grade lesions. Conclusions: VIAM can be a useful alternative to colposcopy when the latter is not available, as it has better sensitivity and equivalent specificity for detecting high-grade CIN. Springer-Verlag, 2010 CIN nationallicence Visual inspection with acetic acid nationallicence Magnavisualizer nationallicence VIAM nationallicence Low-resource settings nationallicence Colposcopy nationallicence Screening nationallicence Aggarwal Pakhee Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, Flat No 1119, Vasto, Mahagun Mansion, 1/4, Vaibhav Khand, 201014, Indirapuram, Ghaziabad, Uttar Pradesh, India aut Batra Swaraj Department of Obstetrics and Gynaecology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India aut Gandhi Gauri Department of Obstetrics and Gynaecology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India aut Zutshi Vijay Department of Obstetrics and Gynaecology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India aut Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 397-403 0932-0067 284:2<397 2011 284 404 https://doi.org/10.1007/s00404-010-1673-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1673-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Aggarwal Pakhee Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, Flat No 1119, Vasto, Mahagun Mansion, 1/4, Vaibhav Khand, 201014, Indirapuram, Ghaziabad, Uttar Pradesh, India aut NATIONALLICENCE 700 1- Batra Swaraj Department of Obstetrics and Gynaecology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India aut NATIONALLICENCE 700 1- Gandhi Gauri Department of Obstetrics and Gynaecology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India aut NATIONALLICENCE 700 1- Zutshi Vijay Department of Obstetrics and Gynaecology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 397-403 0932-0067 284:2<397 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer