caa a22 4500 445311428 CHVBK 20180317142631.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00404-010-1618-7 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1618-7 Pregnancy outcome in systemic lupus erythematosus: Asia's largest single centre study [Elektronische Daten] [Neelam Aggarwal, Ainharan Raveendran, Vanita Suri, Seema Chopra, Pooja Sikka, Aman Sharma] Aim: To evaluate pregnancy outcome in women with systemic lupus erythematosus (SLE). Methods: A total of 71 pregnancies in 35 women with SLE were evaluated for maternal and perinatal outcomes in a tertiary centre of Northern India. Thirty-five pregnancies were evaluated prospectively while details of previous 36 pregnancies in the same women were studied retrospectively. Results: The Mean age of pregnant women with SLE was 26.89±2.7years and 14.57% were nulliparous. The presenting event was arthritis in 60% of the patients; others presented with febrile illness, renal manifestation and cutaneous manifestation. One woman was lupus anticoagulant positive. All women conceived while on disease quiescence period and were continued on the same pre-pregnancy dose of pharmacological agents. Hypertensive disorders of pregnancy were seen in 28.5% while chronic hypertension was seen in 5.6%. The incidence of abortion, preterm deliveries and perinatal loss was 33.8, 29.57 and 12.67%, respectively. Vaginal delivery rate was 47.88 and 18.3% underwent caesarean section. There was no case of neonatal lupus and none had disease flare-up in the postpartum period. Conclusion: A better pregnancy outcome can be expected if clinical remission is achieved and disease activity is adequately controlled prior to pregnancy. Springer-Verlag, 2010 Arthritis nationallicence Azathioprine nationallicence Lupus pregnancy nationallicence Neonatal lupus nationallicence Systemic lupus erythematosus nationallicence Aggarwal Neelam Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Raveendran Ainharan Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Suri Vanita Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Chopra Seema Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Sikka Pooja Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Sharma Aman Rheumatology Wing, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 281-285 0932-0067 284:2<281 2011 284 404 https://doi.org/10.1007/s00404-010-1618-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1618-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Aggarwal Neelam Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Raveendran Ainharan Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Suri Vanita Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Chopra Seema Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Sikka Pooja Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 700 1- Sharma Aman Rheumatology Wing, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh, India aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 281-285 0932-0067 284:2<281 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer