caa a22 4500 445311444 CHVBK 20180317142631.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00404-010-1637-4 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1637-4 High squamous intraepithelial lesion and cancer of lower genital tract in women with anogenital warts [Elektronische Daten] [Miodrag Milojkovic, Dimitrije Milojkovic, Mico Rosso, Bojana Vakanjac] Purpose: The aim of this paper was to determine the incidence of high-grade squamous intraepithelial lesion (HSIL) and cancer of lower genital tract in patients with anogenital warts and their treatment. Methods: Between 1 September 1988 and 30 June 1994, 221 consecutive women with anogenital warts were prospectively examined in the colposcopy outpatient clinic. In 2004, the same group of patients was re-examined. Results: There were abnormal cytological findings in 111 (50.2%) patients; 31 patients (14.0%) had HSIL, and 6 of them (2.7%) had cancer. There were abnormal colposcopic findings in 152 (68.8%) women; 78 women (35.3%) had abnormal histological findings. In the histological findings, HSIL was found in 41 (18.5%) women and cancer in 6 (2.7%). Conclusion: In spite of the fact that anogenital warts are caused by HPV types of low oncogenic risk (6/11), there is an increased incidence of HSIL and cancer in these women. Therefore, women with anogenital warts belong to an increased risk group regarding the cancer of lower genital tract, especially if they are associated with HPV types of a high oncogenic risk. Springer-Verlag, 2010 Anogenital warts nationallicence High squamous intraepithelial lesion nationallicence Genital cancer nationallicence Milojkovic Miodrag Department of Gynecology and Obstetrics, Clinical Hospital Osijek, J. Huttler 4, 31000, Osijek, Croatia aut Milojkovic Dimitrije Department of Gynecology and Obstetrics, Clinical Hospital Osijek, J. Huttler 4, 31000, Osijek, Croatia aut Rosso Mico Department of Gynecology and Obstetrics, Clinical Hospital Osijek, J. Huttler 4, 31000, Osijek, Croatia aut Vakanjac Bojana Department of Gynecology and Obstetrics, Clinical Hospital Osijek, J. Huttler 4, 31000, Osijek, Croatia aut Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 453-457 0932-0067 284:2<453 2011 284 404 https://doi.org/10.1007/s00404-010-1637-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1637-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Milojkovic Miodrag Department of Gynecology and Obstetrics, Clinical Hospital Osijek, J. Huttler 4, 31000, Osijek, Croatia aut NATIONALLICENCE 700 1- Milojkovic Dimitrije Department of Gynecology and Obstetrics, Clinical Hospital Osijek, J. Huttler 4, 31000, Osijek, Croatia aut NATIONALLICENCE 700 1- Rosso Mico Department of Gynecology and Obstetrics, Clinical Hospital Osijek, J. Huttler 4, 31000, Osijek, Croatia aut NATIONALLICENCE 700 1- Vakanjac Bojana Department of Gynecology and Obstetrics, Clinical Hospital Osijek, J. Huttler 4, 31000, Osijek, Croatia aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 453-457 0932-0067 284:2<453 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer