caa a22 4500 445311460 CHVBK 20180317142631.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00404-010-1689-5 doi (NATIONALLICENCE)springer-10.1007/s00404-010-1689-5 Comparison of Pueraria mirifica 25 and 50mg for menopausal symptoms [Elektronische Daten] [Phongthorn Virojchaiwong, Visut Suvithayasiri, Arunporn Itharat] Purpose: To compare Pueraria mirifica 25 and 50mg dosages to relieve menopausal symptoms. Methods: A double-blind study was conducted on 52 hysterectomized women with menopausal symptoms who had an indication for hormone therapy. The women were randomly allocated into two groups receiving either Pueraria mirifica 25mg tablet (Arm A; n=26) or Pueraria mirifica 50mg (Arm B; n=26) for 6months. Menopausal symptoms, physical examination findings, and laboratory data were recorded at baseline. Symptoms were reevaluated at 3 and 6months, while physical and laboratory examinations were evaluated at 1month and at the end of treatment. A modified Green climacteric scale was used to evaluate menopausal symptoms; a score of ≥15 indicated estrogen deficiency. Results: All women completed the study. Mean baseline climacteric scores of women who received 25 and 50mg were: 24.19±9.11 versus 23.19±7.89, respectively (p=0.674). After 3 and 6months of treatment, scores were 17.92±10.40 versus 15.35±8.44 (p=0.332) and 14.08±10.30 versus 12.46±6.38 (p=0.500), respectively. No significant side effects were observed with Pueraria mirifica 25 or 50mg. Conclusions: Both dosages of Pueraria mirifica were similarly effective and safe in the treatment of menopausal symptoms. Springer-Verlag, 2010 Pueraria mirifica nationallicence Modified Green climacteric scale nationallicence Menopausal symptoms nationallicence Virojchaiwong Phongthorn Department of Obstetrics and Gynecology, BMA Medical College and Vajira Hospital, Dusit District, Bangkok, Thailand aut Suvithayasiri Visut Department of Obstetrics and Gynecology, BMA Medical College and Vajira Hospital, Dusit District, Bangkok, Thailand aut Itharat Arunporn Applied Thai Traditional Medicine Center, Faculty of Medicine, Thammasat University, Rangsit Campus, Klong Luang District, Pathumthani, Thailand aut Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 411-419 0932-0067 284:2<411 2011 284 404 https://doi.org/10.1007/s00404-010-1689-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-010-1689-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Virojchaiwong Phongthorn Department of Obstetrics and Gynecology, BMA Medical College and Vajira Hospital, Dusit District, Bangkok, Thailand aut NATIONALLICENCE 700 1- Suvithayasiri Visut Department of Obstetrics and Gynecology, BMA Medical College and Vajira Hospital, Dusit District, Bangkok, Thailand aut NATIONALLICENCE 700 1- Itharat Arunporn Applied Thai Traditional Medicine Center, Faculty of Medicine, Thammasat University, Rangsit Campus, Klong Luang District, Pathumthani, Thailand aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 411-419 0932-0067 284:2<411 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer